Biomedical subjects

S Shalev

Publications and source records attributed to S Shalev.

39 records · Page 3Linked to original sources

PubMedDate not supplied

Verification of radiotherapy treatments: computerized analysis of the size and shape of radiation fields.

An automated technique has been developed for the verification of treatment field size and shape in external beam radiation therapy. Portal images from film or digital on-line imaging system are analyzed, and basic parameters are derived to describe the field size and shape from the contour points on the field boundary. The initial set of parameters included length of the perimeter, area, aspect ratio, and orientation angle. The parameters found for the actual field in the portal image are compared against those calculated for the prescribed field and any discrepancies indicated to the operator. The accuracy of the field parameterization scheme has been tested on a number of on-line portal images with varying fields. The relative error did not exceed a few percent in perimeter and area or 2 degrees in the angle, which should be sufficiently low for the detection of major errors in field shaping.

Computer Simulation↗

PubMedDate not supplied

Grooved phosphor screens for on-line portal imaging.

Video-based systems for on-line portal imaging utilize a metal plate coated with Gd2O2S phosphor at a typical thickness of 500 mg/cm2. A new screen design is proposed wherein the conventional flat phosphor coating is replaced by a much thicker phosphor layer (1000-2000 mg/cm2) penetrated by either lineal grooves or pyramidal holes comparable to the system pixel size. By increasing the surface area of the phosphor, the grooves or holes allow light from deep layers of the phosphor to escape by a process of internal reflection. In addition, the escaping light is strongly forward peaked, improving optical coupling to the video camera. The processes by which grooved screens intensify light output have been modeled in a simple computer program that gives approximate agreement with experiment. Prototype screens have been constructed that provide several times the forward light output of flat screens, and that improve DQE(f) in light photon limited systems for spatial frequencies below 0.4 mm-1.

Computer Simulation↗

PubMedDate not supplied

Legg-Calvé-Perthes disease, protein C deficiency, and beta-thalassemia major: report of two cases.

Legg-Calvé-Perthes disease is an idiopathic osteonecrosis or avascular necrosis of the capital femoral epiphysis and the associated complications thereof occurring in an immature growing child. The association between osteonecrosis of the femoral head and thrombophilia was postulated by Glueck in 1994. We describe Legg-Calvé-Perthes disease associated with protein C deficiency and beta-thalassemia major in two children among a cohort of 79 beta-thalassemia patients treated in our clinic. The association of thrombophilia, aseptic necrosis of the femoral head, and beta-thalassemia has not been previously described in the literature.

Adolescent↗