Search PubMed⌕ Search

Biomedical subjects

S Seyfert

Publications and source records attributed to S Seyfert.

7 recordsLinked to original sources
PubMed1992

Endocrine function in multiple sclerosis.

In 31 patients with multiple sclerosis (MS) the endocrine functions of the hypothalamus, the pituitary and several peripheral endocrine glands were assessed with a combined pituitary test; 3/31 patients had an endocrine disease: one primary hypothyroidism, one primary amenorrhea and one primary male hypogonadism. We found no patient with endocrine disease of the hypothalamus, the pituitary or the adrenals. However, the poststimulatory secretion of cortisol, growth hormone or thyroid-stimulating hormone was impaired in 7/31 patients, suggesting a possible preclinical endocrine insufficiency in these patients.

Adult↗
PubMed1990

Multiple sclerosis and other immunologic diseases.

A characteristic feature of immunologic diseases is their association with each other. For multiple sclerosis (MS), several retrospective studies reported increased as well as expected coincidence rates with other immunologic diseases. We conducted a prospective case-control study of MS patients and healthy volunteers and found 13/101 MS patients and 2/97 controls with such diseases (P = 0.009, chi-square test), as well as 47/88 MS patients versus 31/95 controls with a variety of circulating autoantibodies (P = 0.004, chi-square test). These results speak for an increased coincidence of MS with other immunologic diseases and support the idea that MS is also an immunologic disease.

Adolescent↗
PubMed1979

Accelerated fall in serum bromide level after administration of perchlorate to man.

Five patients intoxicated with bromoureide showed accelerated elimination of bromide from serum after a single dose of perchlorate. It was probably due to increased renal excretion of bromide. Perchlorate has been reported to increase the renal clearance of other monovalent anions by inhibiting their tubular reabsorption and a similar interaction between perchlorate and bromide is suggested. Although perchlorate effectively eliminates bromide it should not replace chloride in the treatment of bromide intoxication, because of the side effects of its repeated administration.

Adult↗
PubMed1978

Abducens palsy after lumbar myelography with watersoluble contrast media.

Five patients who developed abducens palsy after myelography with watersoluble contrast media are reported. These palsies can be compared to abducens palsies after spinal anesthesia and diagnostic lumbar puncture. They are most likely due to the lumbar puncture. The arguments for this explanation are discussed. The experience with these five patients suggests a greater incidence of postpuncture abducens palsy after myelography with watersoluble contrast media than after spinal anesthesia or lumbar puncture. If this first impression is verified, it could point to an additional toxic action.

Abducens Nerve↗
PubMedDate not supplied

Cerebrospinal fluid cell preparation methods. An evaluation.

Although the cells from cerebrospinal fluid are widely used for diagnostic purposes, the cell yield on the microscopic slide is only rarely considered and mostly unsatisfactory. A reevaluation of several preparatory methods showed a very low yield with the Sayk-type chamber, a modest yield with the cytocentrifuge and the best yield with a simple, self-adhering chamber on slides coated with a polycation.

Cerebrospinal Fluid↗