Biomedical subjects
Publications and source records attributed to S Schüller.
Fowl adenovirus particles were studied using negative stain electron microscopy. Upon preparation, some particles collapsed and showed their internal structure. The DNA could be observed as thin parallel lines with a spacing of 25 A, very similar to images of the liquid crystalline DNA in bacteriophage heads and in herpes virus.
17 patients with progressive systemic sclerosis were examined for cardiac involvement using standard ECG, chest X-ray, 24-h Holter ECG, and echocardiography. The control groups consisted of 7 patients with mixed connective tissue disease, 10 patients with systemic lupus erythematosus, and 10 patients with rheumatoid arthritis. The results disclosed a cardiac involvement of 70% using all 4 methods, which is more than is reported in the literature. The data also show that all 4 methods are necessary to diagnose the cardiac involvement. Conduction and rhythm disorders especially are more frequent than in other collagen vascular diseases. The use of calcium channel blockers is discussed as a new therapeutic possibility.