Biomedical subjects

S Scarone

Publications and source records attributed to S Scarone.

76 records · Page 5Linked to original sources

PubMedDate not supplied

Learning capacities during sleep: a preliminary study in a group of schizophrenic inpatients.

The relationship between sleep and learning processes is analysed in a sample of schizophrenic patients, starting from more recent hypotheses about the function of REM sleep in learning and memory processes. This is done by means of two experiments: in the first AA. evaluate the possibility to elicit a simple motor conditional reflex acquired during daytime in different sleep stages. With the second experiment daytime learning performances are evaluated with and without a reinforcement administered during REM sleep. Results for the first experiment underline a qualitative difference between REM and nREM sleep in a reflexological perspective. In nREM sleep the conditional response is better maintained than in REM sleep. The second experiment confirms the possibility to improve daytime learning performances after an additional presentation of learning material in REM. The joint study of sleep abnormalities and learning and cognitive impairment in schizophrenic patients is finally suggested.

Adolescent↗

PubMedDate not supplied

Neurofunctional assessment of lateralized hemispheric asymmetries in affective illness.

Performances of 59 affective patients, 59 schizophrenics and 59 normal controls on the Quality Extinction Test (QET), which has been proven to be valuable for detecting abnormal hemisphere functioning in neurological and psychiatric patients, are presented. Frequencies of the left and right extinctions of the affective patients did not exceed those of normal controls. Compared to schizophrenics, fewer affective patients had left and right extinctions and the number of these extinctions was significantly lower in affective patients. These results would indicate that affective patients do not differ from controls relative to lateralized cerebral malfunctioning as measured by the QET. The differences between affective and schizophrenic patients' QET performances may be explained by differences in the course and chronicity of the disease.

Adult↗

PubMedDate not supplied

Influence of education on WCST performances in schizophrenic patients.

Schizophrenic patients have been widely reported to fail in performing Wisconsin Card Sorting Test (WCST). These data have been mostly interpreted as cognitive difficulties and/or neurofunctional impairment inherent to schizophrenia. Nevertheless, checking sample characteristics, the importance of variables as education appears relevant. In our study we examined schizophrenic patients and controls with low and high educational levels respectively. ANOVA results show significant differences on WCST performances for the variable diagnosis (schizophrenics and controls) and for the variable educational level (low and high educational level). It therefore seems necessary call for caution in interpreting WCST results in schizophrenic patients when educational level is not considered.

Adult↗

PubMedDate not supplied

Lateralized cerebral impairment in schizophrenia. A critical review.

The authors review the more recent areas of research in the field of cerebral lateralized dysfunction in schizophrenia. The different approach consistently suggest a definite degree of abnormality in hemispheric functioning in schizophrenic patients: nevertheless, the heterogeneity of patients' populations, as well as some inherent characteristic of the disease (i.e. duration of the illness, length of hospitalization, duration of drug treatment and psychopathological symptoms) should be taken into the account in order to obtain a more accurate definition of the cerebral impairment in schizophrenia.

Cerebral Cortex↗