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Biomedical subjects

S Sastroamidjojo

Publications and source records attributed to S Sastroamidjojo.

10 recordsLinked to original sources
PubMed1997

Anaemia is associated with reduced productivity of women workers even in less-physically-strenuous tasks.

While many studies show reduced work output in heavy labour with poor nutritional status, data among less-physically-strenuous industrial occupations is scarce. In the present study the output of ninety-two women jute-factory workers over a 1-month period was measured together with haemoglobin, BMI, arm muscle and fat area, physical work capacity (maximum O2 consumption; VO2max), as well as socio-economic, health and activity variables. A significant correlation was found between haemoglobin and work output, which remained significant (P < 0.005) after a multiple-regression analysis with other potentially confounding factors. Anaemic workers and those with VO2max values less than 1.5 l/min were significantly less active at home than non-anaemic workers (P < 0.015). Anaemic women produced an average of 5.3% less in the factory and performed an average of 6.5 h less housework per week.

Adolescent↗
PubMed1997

Longitudinal observation of growth of Vietnamese children in Hanoi, Vietnam from birth to 10 years of age.

OBJECTIVE: To investigate the physical growth of Vietnamese children on a longitudinal basis and with regard to any secular trend. DESIGN: A longitudinal study with four birth cohorts: 1981, 1982, 1983 and 1984 followed up in their homes from birth to 10 y. SUBJECTS: Two-hundred twelve children (128 boys and 84 girls) from two (Hai Ba and Hoan Kiem) out of the four districts in Hanoi. MONITORING OF PHYSICAL GROWTH: Weight, height, feeding practices and diseases were recorded monthly from birth to 12 months, three monthly from 12-36 months, six monthly from 36-72 months, and annually thereafter until 10 y of age. RESULTS: Mean body weight and height of the children at birth was reduced and after the first 3-4 months were comparable to NCHS reference data. Thereafter weight and height fell progressively from the NCHS reference. The most intense period of growth retardation was 15-36 months. The highest proportion of stunting occurred at 21 months (59.4% of males and 58.3% of females). Anthropometric data of Vietnamese children living 1981-1995 in Hanoi were lower than from those living at the same time in Paris but higher than from those living in earlier decades in Vietnam. CONCLUSIONS: The longitudinally-followed children showed growth retardation at birth due to the poor nutritional and health status of their mothers. Children grew well during the first 3-4 months of age, then growth faltering was observed due to inadequate complementary feeding practices. There was a positive secular trend among Vietnamese children.

Anthropometry↗
PubMed1997

Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents.

Different supplementation schemes to build iron stores in female Indonesian adolescents were investigated. Subjects were 273 high-school girls allocated randomly to four treatment groups. During a 3-mo period one group received 60 mg Fe, 750 micrograms retinol, 250 micrograms folic acid, and 60 mg vitamin C per day; a second group received 60 mg Fe, 6000 micrograms retinol, 500 mg folic acid, and 60 mg vitamin C once a week; a third group received 120 mg Fe and the same amount of the other three micronutrients as the second group once a week; and a fourth group received only placebos. All subjects were dewormed and supplement allocation was double blind. Blood samples were collected at baseline, after 2 and 3 mo of supplementation, and 6 mo after the last supplement. After 2 mo of supplementation, groups supplemented weekly and daily showed similar significant improvements (P < 0.001) in hemoglobin and retinol concentrations, and supplementation for 3 instead of 2 mo did not significantly increase these two indicators. After 3 mo, the increase in ferritin was approximately equal to 27 micrograms/L in the daily and 14-15 micrograms/L in the weekly groups (P < 0.001), the latter having a final concentration of 42-45 micrograms/L. At 6 mo postsupplementation there were no significant differences among daily and weekly groups, but the ferritin concentration was still approximately equal to 10-12-micrograms/L higher (P < 0.001) than in the placebo group. The group supplemented weekly with 60 mg Fe complained less about side effects than the other supplemented groups (P < 0.05). Weekly supplementation with 60 mg Fe and 6000 micrograms retinol for 3 mo was optimal for improving the iron status of the adolescents for approximately equal to 9 mo.

Adolescent↗
PubMed1996

Anthelminthic treatment raises plasma iron levels but does not decrease the acute-phase response in Jakarta school children.

The study was conducted to investigate the impact of intestinal helminthiasis and treatment on iron status and acute phase response (APR) among urban Indonesian primary school children, aged 8-11 years old. The prevalence of helminthiasis among these children was; Ascaris lumbricoides, 81.6%; Trichuris trichiura, 88.3%; and mixed infection of A. lumbricoides and T. trichiura, 70.0%. Of 120 children enrolled in the investigation, 59 received a single 400 mg dose of albendazole, and 61 received a placebo. Ten days following treatment, the prevalence of ascariasis and trichuriasis in the treatment group diminished to 0% and 27%, respectively, and in the placebo group to 63.9% and 68.9%. Plasma iron, hemoglobin, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC), interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor (TNF) concentrations were determined prior to the intervention and 10 days after. Plasma iron concentrations and WBC count rose in the treatment group (p=< or =0.05) when compared to baseline status. Increases in hemoglobin concentrations observed in the treatment group 10 days post-treatment were not statistically significant. CRP, IL-1, IL-6 and TNF were found to be within normal limits for both groups both before and after treatment. ESR increased significantly in both treatment and placebo groups when compared the rates measured before treatment. These findings show that treatment with albendazole is associated not only with a decreased worm burden in school children, but also a rise in plasma iron.

Acute-Phase Reaction↗
PubMed1993

Decreased rate of stunting among anemic Indonesian preschool children through iron supplementation.

Effects of iron supplementation on growth and hematological status of Indonesian anemic preschool children with low weight-for-age were investigated. A treatment group (n = 39) received daily supplements of 30 mg Fe and 20 mg vitamin C, whereas a control group (n = 37) received 20 mg vitamin C only for a period of 2 mo. Supplement allocation was double blind. At the start and finish of the study, body weight, height, food intake, and hemoglobin and serum ferritin concentrations were determined. Only the treatment group showed a significant increase in all hematological values (P < 0.001). Height and weight of all children increased (P < 0.01). Increases in height and height-for-age Z score in the treatment group were larger (P = 0.001) than the increase in the control group. The positive effect of iron supplementation on linear growth was not caused by increased food intake, but seems to be influenced by decreased morbidity. Iron supplementation may be a relatively inexpensive way to help decrease the high prevalence of stunting.

Aging↗