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Biomedical subjects

S Sarkar

Publications and source records attributed to S Sarkar.

At least 235 records · Page 13Linked to original sources
PubMed1994

Delivery room management of infants born through thin meconium stained liquor.

A total of 3472 deliveries were studied over a year to evaluate (i) the importance of thin meconium stained liquor (MSL) in the causation of meconium aspiration syndrome (MAS), and (ii) the efficacy of intrapartum plus endotracheal suction at birth in the prevention of MAS due to thin meconium. Two hundred and ninety four (8.5%) of deliveries had meconium stained liquor of which thin MSL was present in 101. MAS occurred in 98 babies. Thin MSL was responsible for 19.4% of cases of MAS. Inspite of intrapartum suction, a high proportion (55-78%) of infants had meconium in the trachea, though thin meconium was found in the trachea significantly less often than thick meconium. Combined intrapartum and endotracheal suction reduced the incidence of MAS due to thin meconium from 26% to 16%. MAS due to thin meconium occurred in asphyxiated as well as vigorous babies inspite of combined suction. Thin meconium accounts for a significant proportion of deliveries with MSL and causes a considerable number of cases of MAS. To prevent meconium aspiration syndrome caused by thin meconium, all neonates born through thin MSL, whether they are asphyxiated or not should undergo intrapartum suction followed by immediate endotracheal suction at birth.

Asphyxia Neonatorum↗
PubMed1994

Localised disturbances associated with primary teeth eruption.

The survey carried out on 201 infants of Calcutta aged 6-12 months to find out the localised disturbances associated with the eruption of the primary teeth, as judged through a questionnaire revealed that the most common disturbance was the inflammation of gums followed by flushing of cheeks, ulcers in mouth, cheek rash and eruption cyst.

Cheek↗
PubMed1993

Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1.

An extract of culture medium of Lentinus edodes mycelia, JLS-S001, significantly blocked the release of infectious herpes simplex virus type 1 (HSV-1) from African green monkey kidney cells. The block in replication was not due to the effect of JLS-S001 on the adsorption and penetration of HSV-1 to the monkey kidney cells. This observation was supported by the fact that JLS-S001 had no significant effect on the expression of virus-specific nucleocapsid proteins in the treated cells. Furthermore, electron microscopy demonstrated the presence of nucleocapsids within the nuclei of the infected and JLS-S001-treated cells. However, the expression of glycoproteins B, C, D, E and I was reduced in the JLS-S001-treated cells. These results suggested that JLS-S001 blocked HSV-1 replication at a late stage in virus replication cycle probably in the assembly and budding of nucleocapsids and subsequent egress from the treated cells.

Adsorption↗
PubMed1993

The use of agarose gels for quantitative determination of fluid saturations in porous media.

The use of agarose gel reference standards for quantifying petrophysical properties in porous media is described. The specific interest is to determine the values of fluid saturations and porosity in oil bearing rocks; the MRI methodology for estimating these properties is discussed. It is shown that the relaxation times of the gel reference standard and the relaxation times of the fluid contained in the porous media affect the estimation process. The determination of porosity and fluid saturations can be greatly simplified if the relaxation times of the reference standard and the relaxation times of the fluid are closely matched. Gel concentration of paramagnetic impurities in the form of copper ions is used to control the longitudinal relaxation properties. The relaxation properties of agarose gels, as a function of agarose and paramagnetic impurity concentrations, have been measured at 2.0 T. The data are well fitted by a simple polynomial in agarose concentration and paramagnetic impurity concentration. Finally, a one-dimensional imaging example of use of agarose gels as reference phantoms is discussed.

Engineering↗
PubMed1993

Acute intravascular haemolysis in glucose-6-phosphate dehydrogenase deficiency.

Thirty-five children with G6PD deficiency, who presented with acute intravascular haemolysis, were evaluated to define its aetiology, clinical features and ultimate outcome. All were boys with ages ranging from 6 months to 12 years. Pallor of abrupt onset and passage of cola-coloured urine were universal presenting symptoms. Incriminating factors responsible for haemolysis include hepatitis (7), malaria (4), bacterial sepsis (3) and drug intake (24), with more than one predisposing condition existing in some children. Marked elevations in serum bilirubin, coinciding with intravascular haemolysis, was a feature in all the seven children with hepatitis. Azotaemia was noted in 20 patients, of whom 14 did not have oliguria. All four children with malaria presented with protracted renal failure. Therapy focused on maintaining a high urine output in those without oliguria. A total of 15 peritoneal dialyses and five haemodialyses were required in six patients with acute renal failure, all of whom were oliguric. Supportive therapy consisted of blood transfusions and treatment of the predisposing diseases. Thirty-two children recovered completely while three died, the cause of death being severe anaemia and congestive cardiac failure, malaria with oliguric renal failure and hepatic encephalopathy, respectively.

Acute Disease↗