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Biomedical subjects

S Sanyal

Publications and source records attributed to S Sanyal.

At least 145 records · Page 8Linked to original sources

Effects of DDT (chlorophenotane) administration on glucose uptake and brush border enzymes in monkey intestine.

A considerable increase occurs in D-glucose uptake and brush border sucrase and lactase activities in the intestine of monkeys treated with a single oral dose of DDT. Brush border alkaline phosphatase activity remains unaffected in the pesticide treated animals. In vitro addiction of DDT has no effect on the sugar absorption and disaccharidase activities.

Administration, Oral↗

Histochemical studies on the long term prostaglandin treatment on adrenal delta5-3beta-hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase activities in rats pretreated with estradiol dipropionate.

Long term Prostaglandin E2 treatment stimulates adrenal weight and steroid output. Indirect studies with histochemical localization of steroidogenic enzymes and hepatocyte glycogen content revealed that in state of adrenal suppression, PGE2 fails to elicit a positive change in steroid output from adrenal cortex, although apparently increases the enzymatic staining reactions. This suggests that the action of Prostaglandin on adrenal steroidogenesis is a pharmacologic one rather than a physiologic response.

3-Hydroxysteroid Dehydrogenases↗

Comparative analysis of cell distribution in the pigment epithelium and the visual cell layer of chimaeric mice.

In chimaeras of both rdrdCC in equilibrium ++ cc and rdrdcc in equilibrium ++CC combinations two types of distribution were observed. In a majority of the chimaeras both retinal layers were chimaeric; whereas in a few cases the pigment epithelium was chimaeric but the visual cell layer was made of ++ cells only. No spatial relation was observed in the distribution of the cells in the two layers. The two eyes of the individuals were nearly always identical with regard to occurrence of chimaerism in the two layers. The findings are discussed in the light of the possible site and mode of expression of the rd gene.

Animals↗

Developmental origin and early differentiation of retinal Müller cells in mice.

During the prenatal development of the retina in mice Müller cells at the initial stage of differentiation show a high level of histochemically detectable non-specific esterase activity. These are the first of the retinal cell types to differentiate and appear at the 11th day of gestation along the vitreal border in the central retina. As development proceeds they appear in more peripheral areas and their perikarya migrate outwardly and become scattered throughout the depth of the retina. Appearance of presumptive Müller cells is followed by rapid growth of the retina and differentiation of the inner retinal layers. With the progress of histogenesis from the central to the peripheral areas the esterase activity in the Müller cells gradually diminishes. The possible significance of early differentiation of Müller cells in promoting growth and histogenesis of retina is discussed.

Animals↗