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Biomedical subjects

S Samuelsson

Publications and source records attributed to S Samuelsson.

46 records · Page 3Linked to original sources

Screening for health risks. How useful is a questionnaire response showing positive family history of myocardial infarction, hypertension or cerebral stroke?

The participants in a community health survey in the Reykjavik area answered the question whether a first-degree relative had had myocardial infarction (MI), hypertension (HT) or cerebral stroke. The mean total serum cholesterol level was 5-10 mg/dl higher in the group with a positive history of MI than in the negative group. The frequency of hyperlipidaemia and the levels of other risk factors measured (blood pressure and body mass index) were similar in both groups. The group with a positive family history (FH) of HT had a mean systolic blood pressure 6-8 mmHg higher and diastolic hypertension (greater than 105 mmHg) on a single measurement twice as frequently as the negative group. The mean systolic blood pressure in the group with positive FH of stroke was 8-10 mmHg higher than in the negative group. The study thus suggests that positive FH of HT or stroke among first-degree relatives is a worthy indication for blood pressure measurements, at least after the age of 40.

Adolescent↗

Life events and mental disorder in an urban female population.

A comprehensive population study of women in Gothenburg, Sweden was carried out in 1968-1969. Altogether 800 women participated in the psychiatric study. Four age strata were studied i.e. women born in 1930, 1922, 1918 and 1914. The same women were re-studied in 1974-1975 (participation rate 84.6%) establishing (1) prevalence of mental disorder, (2) six-year incidence of mental disorder, (3) one-year incidence of mental disorder, (4) occurrence of undesirable life events and (5) connections between life events and one-year incidence of mental disorder. The average prevalence rate was 13.4% for mental disorder with functional impairment, exceeded in lower social groups, by the divorced and the recently widowed. Depressive disorders were most common and autonomic disturbances were the most frequent symptoms. The six-year incidence of mental disorder with functional impairment was 19.5% with raised rate for the divorced and the childless. Undesirable life events increased with the number of children, and decreased with age. The one-year incidence rate decreased with increasing age. The one-year incidence of mental disorder was increased with the amount of undesirable life events.

Adult↗

Community screening for glucose intolerance in middle-aged Icelandic men. Deterioration to diabetes over a period of 71/2 years.

A number of 2203 middle-aged Icelandic men (aged 34-61 years) participated in a health survey in Reykjavik in 1967-68. Blood glucose in the fasting state and during an oral glucose tolerance test (OGTT) showed a unimodal distribution with a slight skewness towards higher values. A positive age gradient was established, which showed an increment of about 7 mg/dl per decade in capillary blood sugar values at 11/2 hours after a 50 g oral glucose load. The age gradient was mostly independent of age-related changes in body weight. A 71/2 year followup of the eligible participants (response rate 80%) showed an overall 1% incidence of metabolic deterioration to "overt diabetes" during this period. Those with positive screening tests (50 g OFTT) at baseline were at greater risk of developing diabetes, but the incidence of deterioration in this group was low, about 1% per year. The progression to diabetes was significantly related to body weight at baseline, suggesting that weight reduction might be beneficial in individuals showing impaired glucose tolerance at medical examination. This study, however, lends support to recent reports showing that mildly impaired glucose tolerance cannot be equated with early diabetes.

Adult↗

The population study of women in Göteborg 1974--1975--the second phase of a longitudinal study. General design, purpose and sampling results.

A study of a population sample of women in Göteborg aged 38--60 years was carried out in 1968--1969. This population sample has been re-studied during the years 1974--1975. Altogether 1302 women participated in this second study, which means 89.1% of those studied in 1968--1969 and 80.3% of those initially sampled. Twenty-six women had died during the interval between the two studies, more than half of them from neoplastic disease. Information is given about those who had moved or were inaccessible at the time of the second study or who refused to participate. The performance of the examination is described and research projects are outlined.

Adult↗