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Biomedical subjects

S Sakaki

Publications and source records attributed to S Sakaki.

At least 181 records · Page 10Linked to original sources

Spontaneous cure of dural arteriovenous malformation in the posterior fossa.

A 28-year-old male with spontaneous disappearance of dural arteriovenous malformation in the posterior fossa ten years after onset is reported. Ligation and excision of the right occipital artery brought about no marked changes in clinical manifestations and the post-operative angiogram. Over nine years after that operation, pulsatile tinnitus disappeared suddenly without any obvious cause and the dural arteriovenous malforamation was absent on the angiogram. The frequency of such an occurrence and some possible mechanisms involved are reviewed and discussed.

Adult↗

Giant cell tumor of the skull.

A 23 year-old female had a giant cell tumor originating in the right temporal bone. A diagnosis was maed by biopsy. Microscopically it was sarcomatous in part. Two courses of radiation therapy, each total dose being 6000 rads and 3000 rads in air, were employed with good subjective response for a short duration. However, the tumor involving the petrous bone and the mastoid process extended, invading the epipharynx and the clivus. The patient died one year after onset.

Adult↗

[A case of cerebral polyuric hyponatremia (author's transl)].

A case of cerebral polyuric hyponatremia was reported. A 64-year-old lady had complained of visual disturbance for 4 years. She was operated upon under the diagnosis of tuberculum sellae meningioma. Sever days following operation tremendous polyuria was senn, i. e. polyuria over 40 l/day, massive sodium wasting in the urine, hyponatremia and severe thirst feeling. These situations could not easily controlled by pitressin, and 2 days after the onset of polyuria the level of sodium in the serum decreased up to 112 mEq/l, the amount of excretion of sodium into urine increased up to 186 mEq/l, and the patient had finally a convulsive seizure followed by loss of consciousness. This hyponatremia was easily controlled by infusion of hypertonic NaCl. The pathogenesis of this condition could not be explained by applying the classical concept of "Diabetes Insipidus" nor "SIADH". This hyponatremia might be the result of massive sodium wasting in the urine. And from the results obtained in our patient, these conditions should be classified in the syndrome of "Cerebral Polyuric Hyponatremia" as reported by Oi et al. It should be emphasized that the measurement of osmorality and level of electrolytes in the serum and urine had to be performed frequently when the postoperative polyuric situation was found, so that the clinical diagnosis could be established in the earlier stage. The clinical diagnosis and differentiation of postoperative disorders in water and electrolytes of central origin were discussed.

Female↗

[Primary osteosarcoma of the skull--a case report (author's transl)].

A case of primary osteosarcoma of the skull is reported in this paper. The patient was a 41-year-old male, who complained of painless swelling of the left upper eyelid and became unable to open his left eye. He was admitted to our hospital on March 27, 1972. A bony hard tumor, fingertip in size, was palpable subcutaneously at the left superior orbital margin. The tumor was inmovable and not tender. Ophthalmological examinations of the left eye revealed disturbance of upward ocular movement without exophthalmos. The ocular fundus showed slight dilatation of the retinal veins and the normal disc. The visual acuity and the visual field appeared intact. X-ray films of the skull showed irregular osteolytic changes in the left orbital roof and the superior orbital margin. Left carotid angiogram showed abnormal vessels forming pools and arterio-venuous fistulae in the osteolytic lesion. An April 5, 1972, surgical removal of the tumor was performed successfully and the dura attached to the tumor was also excised. After operation, chemotherapy and radiation therapy were applied. Histological examination showed osteosarcoma invading the dura. At present, two years and seven months after surgical treatment, the patient is doing well without evidences of recurrence of this disease.

Adult↗