The use of contraceptive pills in treatment of recurrent aphthous ulceration.
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Adolescent↗
Biomedical subjects
S Sadek
Publications and source records attributed to S Sadek.
Specific granulomatous diseases of the gingiva.
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Actinomycosis, Cervicofacial↗
Sphaerophorus necrophorus: laboratory model for the evaluation of chemotherapeutic agents in mice.
Severe necro-purulent lesions were induced in mice following parenteral inoculation of Sphaerophorus necrophorus. Gross and histological changes observed in the lung, liver, and foot pad of infected mice were similar to those occurring naturally in cattle. The lesions could be prevented, cured or significantly reduced by the administration of chemotherapeutic agents such as sulfonamides, potentiated sulfonamide and antibiotics. The application of this novel laboratory model infection in the primary evaluation of potential antibacterial agents is discussed.
Animals↗
Role of candida albicans in patients with and without artifical restorations.
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Candida albicans↗
Effect of sublethal concentrations of the insecticides DDT, Abate and Sevin, applied to 3rd stage larvae of Culex pipiens molestus on certain biological aspects of the mosquito.
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Animals↗
Effect of sublethal concentrations of the insecticides DDT, Abate and Sevin applied to 3rd stage larvae of Anopheles pharoensis on malaria cycle in the adult mosquito.
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Animals↗
Filarial infectivity rate of Culex pipiens molestus subjected to sublethal concentrations of insecticides Abate and Sevin and distribution of infective filaria larvae in mosquito body regions.
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Animals↗
Lesions of dermatophytosis in quinea pigs treated with triamcinolone acetonide: an animal model.
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Animals↗
A modified method for estimation of free thyroxine level and its correlation with the classical thyroid function tests.
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Female↗
The conjectural existence of myxoedema nephropathy.
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Adolescent↗
Is cyclosporine toxic to the heart?
Cardiotoxicity caused by cyclosporine was studied in experimental rats by the uptake of radiopharmaceuticals (technetium 99m-labeled pyrophosphate and indium 111-labeled antimyosin) and histologic examination of heart tissues. A dose of 50 mg/kg (body weight) of cyclosporine and an equal volume of vehicle (cremophor-EL) were injected into the rats subcutaneously for 7 or 11 consecutive days. A statistically significant difference (p < 0.05) was noted between the uptake of the radiopharmaceuticals in the hearts of cyclosporine-treated rats compared to the control rats. For 99mTc pyrophosphate, the cardiac uptake ratios of cyclosporine-treated rats to control rats were 2.13 and 4.08 for 7-day and 11-day treatment periods, respectively. For 111In antimyosin, the ratios were greater than 2 for both 7-day and 11-day treatment periods. Histologically, vacuoles were found in single or focal groups of myocytes with interstitial edema in the hearts of cyclosporine-treated rats compared to the control rats. The results of both the uptake of the radiopharmaceuticals and the histologic evidence indicate cell injury in the hearts of cyclosporine-treated rats. Cyclosporine therefore seems to be toxic to the heart tissue.
Animals↗