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Biomedical subjects

S S Sutherland

Publications and source records attributed to S S Sutherland.

42 records · Page 3Linked to original sources
PubMed1982

A study of cattle infected with Brucella abortus and which showed aberrant serological reactions.

Sixty cows, 48 of which had been vaccinated with live Brucella abortus strain 19 (S19) or with killed B. abortus strain 45/20 (S45/20) and 12 of which were unvaccinated animals, were challenged with B. abortus strain 544. Ten of the 27 cattle found to be infected after challenge showed aberrant serological reactions to the Rose Bengal Plate test, serum agglutination test and/or complement fixation test. These 10 cattle were all previously vaccinated with S19 or S45/20. It was concluded that infection in cattle vaccinated with S19 or S45/20 may be more difficult to detect than infection in animals that have no history of vaccination.

Animals↗
PubMed1982

Comparison of the complement fixation test and the indirect hemolysis test for cattle vaccinated and infected with Brucella abortus.

The complement fixation test (CFT) and indirect hemolysis test (IHLT) were applied to sera collected from 60 cattle challenged with Brucella abortus 544. Of the 60 cattle, 48 were vaccinated with either B. abortus 19 or B. abortus 45/20 as calves or as adults. The remaining 12 cattle were not vaccinated. Of the 27 sera from cattle found to be infected, 9 showed aberrant reactions to the CFT. The advantages of the IHLT for these cattle were as follows. After challenge, the titers to the IHLT became positive earlier than or at the same time as the titers to the CFT, they persisted longer than the titers to the CFT, and they failed to show prozone reactions, which are a problem with the CFT. An additional advantage was that before challenge and after vaccination with strain 19, the titers to the IHLT rose later and declined earlier than the titers to the CFT. We concluded that the CFT used in conjunction with the IHLT improves the detection of infected cattle.

Animals↗
PubMed1981

The effect of challenge with virulent Brucella abortus on beef cattle vaccinated as calves or adults with either Brucella abortus strain 19 or 45/20.

Groups of female calves were vaccinated subcutaneously with the standard dose of Brucella abortus strain 19 (S19) or with B. abortus 45/20 (S45/20). These calves and non-vaccinated control calves were mated at 15 months of age and challenged by way of the conjunctival sac with B. abortus strain 544 (S544). The incidence of abortion, stillbirths, weanling calves and healthy calves was observed after challenge and specimens were collected for culture at parturition and slaughter. Fifteen healthy calves were born to 18 animals vaccinated with S19, 12 were born to 18 animals vaccinated with S45/20 and 2 were born to 8 animals that were not vaccinated. B. abortus was isolated from 5 of the animals vaccinated with S19, 13 of the animals vaccinated with S45/20 and 9 of the 12 animals that were not vaccinated. Only one of the 5 infected animals vaccinated with S19 was vaccinated as an adult.

Animals↗
PubMed1981

The association between body strike and dermatophilosis of sheep under controlled conditions.

The association of dermatophilosis with body strike of sheep caused by Lucilia cuprina was studied in a controlled environment. When sheep with areas of wet normal fleece and areas of wet fleece containing scabs induced by infection of the skin with Dermatophilus congolensis were exposed to gravid L. cuprina the files oviposited only on dermatophilosis-affected areas. In wet dermatophilosis-affected fleece, naturally oviposited L. Cuprina eggs hatched and the larvae developed to the second instar stage. Artificially implanted L cuprina eggs hatched in both wet dermatophilosis-affected fleece and wet normal fleece. In wet dermatophilosis-affected fleece the larvae from implanted eggs developed normally but in wet normal fleece they did not develop past the first instar stage. It was concluded that wet but otherwise uncomplicated dermatophilosis lesions are attractive to L. cuprina and provide sufficient protein to allow larval development to take place.

Actinomycetales Infections↗
PubMed1978

Evaluation of new and currently used diagnostic procedures for bovine brucellosis.

The indirect haemolysis test (IHLT) and the rough antigen complement-fixation test (RCFT) were compared with several conventional tests using serum samples from 9 cows known to be infected with Brucella abortus. In 7 cows all the tests except the RCFT (which was developed to detect antibodies resulting from 45/20 vaccination) became positive and remained so until the cows were autopsied 6 months after infection. In the other 2 cows the Rose Bengal test was occasionally negative and the titre of the serum agglutination test only reached 100 iu briefly. The routine complement-fixation test, the IHLT and the anti-bovine globulin test reached diagnostic levels at most of the weekly test intervals but occasional low titres occurred in them all. Only very low or negative titres were detected by the RCFT.

Animals↗