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Biomedical subjects

S S Sheth

Publications and source records attributed to S S Sheth.

At least 37 records · Page 2Linked to original sources
PubMed1995

MR marrow signs of iron overload in transfusion-dependent patients with sickle cell disease.

Magnetic resonance (MR) marrow signal in the axial and appendicular skeleton of 13 transfusion-dependent and chelated pediatric patients with sickle cell anemia (SSD) was compared with marrow signal in six non-transfusion-dependent patients with SSD. Hepatic, pancreatic, and renal MR signal were also evaluated. Indication for hypertransfusion therapy was primarily prior history of stroke. Transfusion-dependent patients had evidence of iron deposition throughout the imaged marrow and the liver, despite deferoxamine chelation therapy. Non-transfusion-dependent patients did not demonstrate grossly apparent signs of iron overload. Red marrow restoration was present in the spine, pelvis, and long bones and, in some patients, within the epiphyses. Marrow edema secondary to vaso-occlusive crises was evident in the metaphyses and diaphyses of long bones in areas of both red and fatty marrow and was best seen using fat-saturated T2-weighted imaging techniques.

Adolescent↗
PubMed1995

Transvaginal trucut biopsy in patients with abdominopelvic mass.

OBJECTIVE: To perform an abdominopelvic or pelvic mass biopsy as an office procedure, as an alternative to laparoscopic biopsy. METHODS: A transvaginal trucut biopsy using a disposable biopsy needle was carried out in 5 cases. RESULTS: The biopsy gave a clear diagnosis of ovarian cancer in 2 cases, non-tubercular inflammation in 2 cases and tuberculosis in 1 case. CONCLUSIONS: In the developing world, transvaginal trucut biopsy is an important method for diagnosis.

Adenocarcinoma↗
PubMed1995

Vaginal hysterectomy following previous cesarean section.

OBJECTIVE: To determine whether hysterectomy by the vaginal route is safe and feasible in patients with previous cesarean section. METHODS: A retrospective study of the records of private and public hospital patients who underwent vaginal hysterectomy performed by the senior author. Two hundred twenty patients who had had previous cesarean sections were compared with a control group of 200 patients who had not had previous pelvic surgery, with special reference to operative difficulties, intraoperative complications, surgical time and length of hospital stay. RESULTS: It was possible to perform vaginal hysterectomy safety in patients with previous cesarean sections. Three of 200 (1.5%) patients had inadvertent intraoperative urological trauma because of dense adhesions. CONCLUSIONS: The vaginal route is the route of choice for performing a hysterectomy in patients with previous cesarean section.

Adult↗
PubMed1993

Vaginal hysterectomy for myomatous polyp.

Vaginal hysterectomy was performed in 28 perimenopausal women with large myomatous polyps protruding from the cervix. The vaginal route was selected for hysterectomy instead of the usual abdominal approach, based on assessment made after examination under anesthesia following polypectomy. All patients made an uneventful recovery. In women who need hysterectomy, we recommend that removal of myomatous polyps vaginally should be followed by a thorough assessment for deciding the route of hysterectomy. In most cases, the choice would be vaginal hysterectomy, sparing the women the trauma of an abdominal operation.

Blood Loss, Surgical↗
PubMed1991

The place of oophorectomy at vaginal hysterectomy.

A series of 740 vaginal hysterectomies with attempted vaginal oophorectomy is presented and compared with 700 vaginal hysterectomies without oophorectomy. Vaginal oophorectomy was successful in 94% of the patients. Factors influencing the success include obesity, nulliparity, decreased vaginal access and space, lack of uterine descent, increased uterine size and tubo-ovarian disease. These have been analysed and the recognition and management of technical difficulties are described. There was no morbidity attributable to the vaginal oophorectomy. With experience and appropriate technique suitable women can be offered prophylactic oophorectomy at the time of vaginal hysterectomy.

Female↗
PubMed1991

Cerebrospinal dehydrogenases in central nervous system infections.

Cerebrospinal fluid (CSF) dehydrogenases were studied in 42 controls, 23 children with pyogenic meningitis, 22 with tuberculous meningitis and 19 with encephalitis to assess their usefulness in differentiating between the different central nervous system infections. CSF-LDH and ICD activity was increased in CNS infections (p less than 0.0001), LDH being significantly higher (p less than 0.001) in pyogenic meningitis than in tuberculous meningitis or encephalitis. However, ICD activity was significantly different in each of these conditions (p less than 0.001). The dehydrogenase activity declined with subsequent clinical improvement, in all children with meningitis. A significant direct relationship was found between the enzyme activity and CSF protein content as well as total cell count. The 95% confidence interval confirms the utility of assaying CSF dehydrogenase activity to differentiate various CNS infections, thus improving the diagnostic ability.

Acute Disease↗
PubMed1989

The place of laparoscopy in women with ascites.

Laparoscopy was performed in 70 women with ascites of unknown origin, and in 56 a visual diagnosis, aided by biopsy, was made. There was carcinoma in 32, tuberculosis in 20 and cirrhosis of the liver in four. No abnormality was seen in 14.

Abdominal Neoplasms↗