Penicillin hypersensitivity: detection by basophil response to challenge.
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Basophils↗
Biomedical subjects
S S Resnik
Publications and source records attributed to S S Resnik.
Basophil degranulation induced by oral poison ivy antigen.
Seven subjects shown by patch test to be sensitive to poison ivy oleoresin were challenged with graded oral doses of ivy extract. In each instance the circulating basophil leukocytes showed significant degranulation within one hour of challenge. This finding was interpreted as evidence of the presence of immediate-type circulating antibody to ivy antigen in these subjects. No drop in the absolute basophil count was noted, but with higher oral doses the degranulation persisted for several days. Thirteen control subjects showed no change in the basophil morphology or count, indicating that the resin at these levels was not toxic to this cell. All but one of the sensitive subjects showed objective patch test evidence of hyposensitization following the intensive three-week course of oral poison ivy antigen.
Antigens↗
Surgical refinements of the hairline in hair transplant surgery.
A hairline placed too low on the forehead is the most common error in hair transplant surgery, and misdirection of grafts is the second most common. Correction of these and other errors in this subtle surgery is difficult and challenges the surgeon's artistic talents. In most cases, a natural appearance can be achieved.
Esthetics↗