Effect of route of administration of dioxane on hepatic mixed function oxidase enzymes in mice.
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Animals↗
Biomedical subjects
S S Pawar
Publications and source records attributed to S S Pawar.
Hepatic and renal microsomal electron transport reactions in endrin treated female guinea pigs.
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Aminopyrine↗
Induction of the hepatic microsomal mixed function oxidase system in mice by p-dioxane.
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Animals↗
Alterations in the toxicity of thiodemeton due to the pretreatment of inducers, substrates and inhibitors of mixed function oxidase system.
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Acetanilides↗
NADH dependent aminopyrine N-demethylation and lipid peroxidation during Baygon intoxication in hepatic and extrahepatic guinea pig tissues.
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Aminopyrine N-Demethylase↗
Microsomal mixed function oxidase system in human placenta: substrate interactions with cytochrome P-450.
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Adult↗
Alteration in mixed function oxidase system during thiodemeton (o-o diethyl S-2(ethylthio) ethyl phosphorothioate) toxicity.
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Animals↗
Microsomal mixed function oxidase system in human placenta--lipid peroxidation.
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Adult↗
Stimulation of mixed function oxidase system by ascorbic acid.
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Animals↗
Microsomal mixed function oxidase system in human placenta: electron transport constituents & aminopyrine N-demethylation.
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Aminopyrine N-Demethylase↗
The toxicity of endrin and the effect of pretreatment of phenobarbital and hexobarbital on mortality in four fresh water fishes.
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Animals↗
Dioxane toxicity & hepatic mixed function oxidase enzymes in mice.
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Animals↗
Oral intoxication of insecticides & hepatic mixed function oxidase system in rats.
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Animals↗
Hepatic microsomal mixed function oxidase system during toluene treatment and the effect of pretreatment of phenobarbital in adult rats.
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Animals↗
Dioxane-induced changes in mouse liver microsomal mixed function oxidase system.
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Animals↗
Effects of atropine sulphate treatment on hepatic mixed function oxidase system during Baygon intoxication.
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Animals↗
Phenobarbital induced effect on pulmonary and hepatic microsomal ethylmorphine N-demethylase and lipid peroxidation during oral intoxication of organic solvents in rats.
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Animals↗
Hepatic drug metabolism and lipid peroxidation in thiamine deficient rats.
In vitro metabolism of aminopyrene, ethylmorphine (Type I substrates), N-methylaniline and acetanilide (Type II substrates) in liver microsomal fraction from thiamine deficient male and female rats was studied. No significant change in microsomal protein content was noticed during the period of thiamine deficiency. However, a significant increase in the in vitro oxidation of aminopyrene, ethylmorphine, N-methylaniline and hydroxylation of acetanilide was observed. The NADPH linked and ascorbate induced lipid peroxidation was also increased during thiamine deficiency. The levels of NADPH cytochrome c-reductase, cytochrome b5 and heme were noticeably increased in thiamine deficient animals as compared to normal rats. Phenobarbital treatment induced the activities of all drug enzymes and inhibited the lipid peroxidation in either sex during the period of thiamine deficiency. It appears that thiamine intake is an important determination in drug metabolism and lipid peroxidation.
Acetanilides↗