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Biomedical subjects

S S Patterson

Publications and source records attributed to S S Patterson.

At least 37 records · Page 2Linked to original sources

Comparison of Dycal and formocresol pulpotomies in young permanent teeth in monkeys.

This study compared Dycal and formocresol pulpotomies on young healthy permanent teeth with respect to continued dentinogenesis and root end development. Pulpotomy was performed on a total of forty permanent teeth with incompletely developed roots in three young stump-tailed monkeys (Macaca speciosa). Twenty teeth were treated with Dycal and twenty with formocresol. At the end of the experimental periods the animals were killed and the specimens were prepared and sectioned en bloc for histologic examination. The interval between treatment and death ranged between 7 and 797 days. Before each experimental procedure a Procion vital dye was administered as a marking agent for continued root development. Twelve of twenty teeth treated with Dycal and seventeen of twenty teeth treated with formocresol were judged to be successful as evidenced by continued root development, absence of periapical pathoses, and the presence of noninflamed or only mildly inflamed pulps. Brown and Brenn staining showed bacteria within the pulps of the teeth that failed. All but one of the teeth in this study showed evidence of continued root development as confirmed by Procion labeling.

Animals↗

Response of periapical pathosis to endodontic treatment in monkeys.

Response of induced periapical lesions in monkeys to a conventional endodontic technique was investigated at varying periods ranging from 15 to 365 days after treatment. The findings indicate that response to treatment is influenced by the extent of the root canal filling, the time lapse between treatment and death, and the presence or absence of bacteria in the apical portion of the canal.

Animals↗

Effect of cobalt-60 radiation on the pulp of restored teeth.

The effect of cobalt-60 teletherapy on the pulps of restored teeth of monkeys was studied. Gold crowns and amalgam and composite resin restorations were placed in 28 teeth of two Macaca speciosa monkeys. One monkey then received cobalt-60 radiation to both maxillary and mandibular teeth and bones, with a total dose of 7,600 rads. Decalcified semiserial paraffin sections, 7 mum thick, of the teeth and supporting tissues were prepared and stained with hematoxylin and eosin. Microscopically, there was no discernible difference between the irradiated and the non-irradiated pulps.

Animals↗

Clinical, radiographic, and histological study of endodontically treated retained roots to preserve alveolar bone.

Endodontically treated, submerged roots in two Macaca speciosa monkeys were studied clinically, radiographically, and histologically. The roots were successfully covered by soft tissue, except in two areas. In several sites, radiographic evidence of bone formation was observed; this was confirmed by histologic examination. Bone formation coronal to the submerged roots was not a predictable occurrence. Even though epithelium and inflammation commonly occurred over the amputation sites, their presence did not seem to affect bone formation.

Alveolar Bone Loss↗