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Biomedical subjects

S S Cutler

Publications and source records attributed to S S Cutler.

27 records · Page 2Linked to original sources

Serial exercise testing after coronary artery bypass surgery.

To determine the duration of functional benefit from coronary bypass surgery, 111 patients with angina pectoris were serially evaluated by standard exercise testing prior to and for up to 4 years after surgery. Exercise testing 6 to 18 months after surgery showed greater heart rate-blood pressure product at peak work load, improved work capacity, and less symptomatic and electrocardiographic evidence of ischemia than was demonstrated preoperatively. Twenty patients were tested 37 to 48 months postoperatively and showed improved exercise performance in comparison with preoperative results, but the frequency of positive tests during this period no longer differed. Thus, improved exercise performance appears to persist for at least 4 years after coronary bypass surgery.

Angina Pectoris↗

Sicca complex and cholangiostatic jaundice in two members of a family probably caused by thiabendazole.

An entire family (father, mother, and three daughters) were given thiabendazole because one of the children had acquired pinworm infestation. The mother and one daughter (non-infected) developed a sicca complex (keratoconjunctivitis sicca and xerostomia) accompanied by cholangiostatic jaundice. Sjögren's syndrome is an autoimmune disease and presents many immune mechanism aberrancies. An association between autoimmune liver disease and sicca complex has been reported. Labeled mitochondrial antibodies bound to the parotid duct have been noted in patients with autoimmune cholangiostatic jaundice and such antibodies may be similar to the antibody against salivary duct found in Sjögren's syndrome. It is suggested that in these two patients, thiabendazole may have acted as a hapten and by binding to the body protein induced the production of autoantibodies which may have acted against the biliary epithelium, the salivary duct epithelium, and the lacrimal gland ducts.

Adolescent↗

Unclassified benign tumor of the rib. Osteochondroblastoma.

A previously unclassified benign tumor of the rib is reported. The tumor was found in a 21-year-old black woman who presented herself with chest pain. After its radiologic discovery the exophytic tumor was resected. Histologically, it was composed of two seemingly independent components. The more central portion of the tumor was principally an osteoblastoma, while the more peripheral and greater mass of the neoplasm was chondroblastic. The name "osteochondroblastoma" is proposed for this lesion.

Adult↗