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Biomedical subjects

S S Cross

Publications and source records attributed to S S Cross.

117 records · Page 7Linked to original sources

Classification of mouse thymic virus as a herpesvirus.

Classical herpesvirus particles were observed by thin-section electron microscopy in thymus tissues from mice inoculated with mouse thymic virus. Intranuclear particles measured approximately 100 nm in diameter, and cytoplasmic and extracellular particles measured 135 nm in diameter. The morphology of mouse thymic virus particles together with its properties of heat and ether lability suggest that thymic virus should be classified as a member of the herpesvirus group.

Journal Article↗

An antiviral sesquiterpene hydroquinone from the marine sponge Strongylophora hartmani.

A new sesquiterpene hydroquinone 1, which we call strongylin A, was isolated from the marine sponge Strongylophora hartmani. Its structure was determined through spectroscopic methods, including 2D-13C homonuclear correlation spectroscopy (INADEQUATE). Both 1 and its acetate derivative are active in in vitro assays against the P-388 tumor cell line and influenza strain PR-8.

Animals↗

Fractal geometric analysis of the renal arterial tree in infants and fetuses.

Fractal geometry is a useful method of quantitating the space-filling properties of complex objects and has a particular advantage in pediatric pathology because it is independent of organ size. The fractal dimensions of angiographic images of 44 renal arterial trees from 23 consent pediatric autopsies were measured by the box-counting method. The mean fractal dimension was 1.64 and all values were greater than the topological dimension (one), indicating that the renal arterial tree in fetuses and infants has a fractal element to its structure. There was no significant association with size of the kidneys, confirming the size-independent nature of the fractal dimension. There was no significant association with age of the subject, and the mean value was not significantly different from values obtained in studies of adult kidneys, suggesting that the degree of branching, at a lobar and lobular level, does not increase after about the 21st week of gestation. The results are compatible with a diffusion-limited aggregation model of development.

Adult↗