Biomedical subjects
Publications and source records attributed to S S Arifov.
A computer audiometer has been designed on the computer using program "Audiometry". No special devices are needed. This computer audiometric complex can perform all kinds of behavioral audiometry: tonal threshold, suprathreshold, speech and in a free sound field.
The study of the autonomic status of the body in 38 patients with different forms of chronic purulent otitis media (CPOM) has demonstrated that patients with exacerbation or complication of CPOM were for the most part sympathotonics and normotonics. The former had more persistent disease with more frequent recurrences.
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Local sorption therapy of postoperative wounds in patients with exacerbation of otitis media purulenta chronica with gelecel stimulates cleansing of the wounds from pyonecrotic substances on postoperative day 2-3. Regeneration in the trepanation or radical cavity starts on day 2-3. Intoxication ceased 2 days earlier compared to the procedure with the use of medical gauze. To prevent dehydration of the soft tissue gelecel should be applied on postoperative day 5-6.
Plasma levels of medium molecular peptides (MMP) were measured and Paramecium test was made in 28 patients with acute otitis media purulenta (AOMP). Of these, 18 patients had complicating mastoiditis. The baseline results of both tests correlated with clinical symptoms of systemic endogenic intoxication. Paramecium test returned to normal after one day of treatment. Informative value of this test fell with detoxication contrary to plasma MMP value which correlated with the degree of intoxication and remained informative through detoxication being able to show even residual subclinical toxicity. The MMP test is a method of choice in assessing intoxication in patients with AOMP and its complications.
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The examination of 90 patients referred to hospital for otitis media purulenta (OMP) and 25 healthy subjects included assessment of lipid peroxidation by content of malonic dialdehyde and intensity of chemoluminescence. Enzymes of antioxidant system were also measured (superoxide dismutase and catalase in blood plasma and wash-offs from the acoustic meatus and postoperative cavities). The measurements gave different values for the above parameters for healthy and OMP subjects. Conventional treatment reduced levels of LPO products and raised the activity of antioxidant enzymes, but control values were reached only in adjuvant parenteral administration of lipostabil and local administration of alpha-tocopherol. Also, earlier relief of clinical symptoms shortened the hospital stay.
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A clinical classification of lichen ruber pilaris is presented, based on the authors' observations of 30 cases. Three types of such lichen may be distinguished, characterized by a specific clinical picture, course of skin process, and prediction of the process course: adult, childhood, and atypical types.
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Studies with the use of Fe2(+)-induced chemiluminescence of apo-beta-lipoproteins and electron histochemistry have revealed that PUVA therapy and vitamin A high doses enhance lipid peroxidation and activate adenylate cyclase in patients with Devergie's disease. This finding permits a conclusion on the usefulness of enhancing lipid peroxidation in order to reduce cellular mitotic activity.