Biomedical subjects
S Russian
Publications and source records attributed to S Russian.
[Evaluation of a rapid and simple ambulatory method for the determination of HbA1c in diabetic children].
The aim of this study was to compare a simply and quick outpatient method for the determination of HbA1c (DCA 2000 Bayer) to a laboratory immunoturbidimetric method (B M Hitachi 911). We have determined HbA1c in 139 subjects (120 diabetics and 19 healthy controls, 81 males and 58 females, mean age ( +/- DS) 14.4 +/- 6.41 years, range 2-40) with the two methods at the same time. The HbA1c normal range, determined by DCA 2000 and by laboratory method, were 4-5.2% and 4.5-6% respectively. The HbA1c values determined with both methods were significantly correlated (r = 0.91; p < 0.001). In 16 diabetic patients, chosen for their reliability, the HbA1c values determined by DCA 2000 were significantly correlated to the last two month mean glycemic level preceding the test. In 14 healthy subjects HbA1c was determined simultaneously by DCA 2000 in capillary and venous blood samples. The values were similar. The DCA 2000 method showed to be reliable, simply to use, no traumatic and ideal for pediatric outpatient use.