Search PubMed⌕ Search

Biomedical subjects

S Rowlands

Publications and source records attributed to S Rowlands.

At least 37 records · Page 2Linked to original sources
PubMed1993

Estimated date of delivery from last menstrual period and ultrasound scan: which is more accurate?

The aim of this study was to determine which is the more accurate predictor of the date of delivery for pregnant women in a community-based population: a calculation based on the last menstrual period or a prediction based on the measurement by ultrasound scanning of well-recognized fetal characteristics. A prospective study was conducted of 225 consecutive women reporting their pregnancy in a semi-rural general practice; 106 women were included in the analysis. The results showed that in over 50% of cases the estimated date of delivery derived from the ultrasound scan was more accurate than that derived from the last menstrual period, whatever the discrepancy between the two predictions. It can be concluded that all professionals involved with antenatal care should ignore the estimated date of delivery derived from the last menstrual period once a satisfactory scan has been obtained.

Female↗
PubMed1987

Pill-taking routine.

Explore the source record for details and available documents.

Contraceptives, Oral↗
PubMed1986

A possible mechanism of action of danazol and an ethinylestradiol/norgestrel combination used as postcoital contraceptive agents.

Twenty-seven women requesting postcoital contraception were randomly allocated to take an ethinylestradiol/dl-norgestrel combination or danazol. Urine specimens were assayed for luteinising hormone (LH) and pregnanediol-3-glucuronide (P3G) levels from the day of the postcoital treatment to the next period. In addition, the urine samples of these recruits and 12 additional women were assayed for the Beta-subunit of human chorionic gonadotropin (B-hCG). A consistent pattern of alteration in urinary steroids was lacking, indicating a heterogeneous effect on ovarian function. There was no evidence of early pregnancy in successfully treated cases. We suggest that the main mechanism of action of these drugs is at the endometrial level.

Chorionic Gonadotropin↗
PubMed1984

Fibrinogen and the ultralong-range interaction of human erythrocytes.

Fibrinogen, purified by a new method, does not transmit the ultralong-range interaction of erythrocytes. It can be converted into a transmitter by the addition of a preparation of clotting factors used clinically in the treatment of hemophilia B. It is suggested that the addition of the clotting factors induces a conformational change in fibrinogen, which can then polymerize.

Blood Coagulation Factors↗
PubMed1983

Planar Brownian motion in the presence of an attractive force.

The two-dimensional Brownian motion of circular disks is considered where these join to form groups whenever they touch. The total number of groups Nt is considered as a function of time. An upper bound for Nt-1 is derived and compared to the experimental movement of erythrocytes. Cells at pH = 7.4 and pH = 6.3 are shown to have a group count that respectively exceeds and falls below the plotted bound. This provides evidence that live cells have a tendency to coalesce that is not explained by Brownian motion only.

Biophysical Phenomena↗
PubMed1983

Conversion of albumin into a transmitter of the ultra long-range interaction of human erythrocytes.

Previous experiments in our laboratory and elsewhere have shown that extended macromolecules of high molecular weight are needed in the suspending medium to transmit the quantum-mechanical coherent interaction of human erythrocytes. Albumin, a globular protein, does not transmit the interaction at physiological concentrations. Albumin can be converted into a transmitter by preheating a solution of albumin to 62 degrees C for 20 min. Such treatment unravels the tertiary structure of albumin and allows it to polymerize.

Cell Communication↗
PubMed1983

Side effects of danazol compared with an ethinyloestradiol/norgestrel combination when used for postcoital contraception.

A postcoital contraceptive with a lower incidence of nausea and vomiting than oestrogen-progestogen combinations would be a significant advance. During a nine-month period, 101 women were treated at the Margaret Pyke Centre in London with either an oestrogen-progestogen combination or with danazol. A comparison of the side effects of each drug is reported. Those treated with danazol were six times less likely to experience nausea and none vomited. With the exception of breast symptoms, other side effects were five times less common in women receiving danazol. These differences give danazol a clear advantage in terms of patient acceptability. Further experience will enable the efficacy of danazol to be evaluated and so determine whether this drug should become the preferred hormonal postcoital treatment.

Adult↗
PubMed1982

Morning-after pills.

Explore the source record for details and available documents.

Contraceptives, Postcoital↗