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S Rosenthal

Publications and source records attributed to S Rosenthal.

174 records · Page 10Linked to original sources
PubMedDate not supplied

Supervised interpretation of echocardiograms with a psychological model of expert supervision.

We have developed a collaborative scheme that facilitates active human supervision of the binary segmentation of an echocardiogram. The scheme complements the reliability of a human expert with the precision of segmentation algorithms. In the developed system, an expert user compares the computer generated segmentation with the original image in a user friendly graphics environment, and interactively indicates the incorrectly classified regions either by pointing or by circling. The precise boundaries of the indicated regions are computed by studying original image properties at that region, and a human visual attention distribution map obtained from the published psychological and psychophysical research. We use the developed system to extract contours of heart chambers from a sequence of two dimensional echocardiograms. We are currently extending this method to incorporate a richer set of inputs from the human supervisor, to facilitate multi-classification of image regions depending on their functionality. We are integrating into our system the knowledge related constraints that cardiologists use, to improve the capabilities of our existing system. This extension involves developing a psychological model of expert reasoning, functional and relational models of typical views in echocardiograms, and corresponding interface modifications to map the suggested actions to image processing algorithms.

Algorithms↗
PubMedDate not supplied

Attachment over time.

Continuity in attachment classification from infancy to late adolescence was examined and related to autobiographical memories of childhood, divorce, and maladjustment. Eighty-four White middle-class children (48 girls) were seen in a modified Strange Situation at 12 months and given the Adult Attachment Interview at 18 years. In addition, data were collected on 13-year-olds' childhood recollections as well as adolescent, mother, and teacher ratings of maladjustment at 13 and 18 years of age. Divorce status of parents also was obtained. Results indicated no continuity in attachment classification from 1 to 18 years of age and no relation between infant attachment status and adolescent maladjustment. Divorce was related to 13-year-olds' childhood recollections as well as to insecure attachment status at 18 years. Eighteen-year-olds with insecure attachment classification were more likely to rate themselves as maladjusted. The results support the idea of attachment as an evolving representation dependent upon the nature of the family environment as indexed by divorce.

Adolescent↗
PubMedDate not supplied

Phase II study of maytansine in patients with advanced lymphomas: an Eastern Cooperative Oncology Group pilot study.

During phase I trials with maytansine some activity against lymphoma and lymphocytic leukemia was noted. Therefore, a phase II trial of maytansine in patients with advanced lymphomas refractory to conventional chemotherapy was begun. There were three partial responders (10%) among 31 patients entered in the trial. Toxicity was acceptable; gastrointestinal and neurologic side effects were the most common. Little myelotoxicity and no hepatotoxicity were observed. We conclude that maytansine has very limited activity in heavily pretreated patients with Hodgkin's disease and non-Hodgkin's lymphomas.

Adult↗