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Biomedical subjects

S Roi

Publications and source records attributed to S Roi.

2 recordsLinked to original sources

[Liver injuries].

The analyses of literature data on the results of the treatment of patients with mechanical injuries of the liver have been done. Analyses of 458 cases of open and closed liver traumas made it possible to determine 2 clinical forms of liver injuries: hemorrhagic and peritoneal. The separate subforms of traumatic liver disease in isolated multiple and combined injuries are determined. A diagnostic role of various methods was evaluated. Use of laparoscopy in 17 patients has exposed a superficial character of liver injuries and allowed not to perform surgery. Use of low-frequency ultrasound and polymeric adhesive sulfacrilat for the treatment of liver wounds in 63 patients has decreased the rate of postoperative complications to 18%, and the rate of mortality in mechanical liver injuries to 11.4% (in patients with mechanical liver injuries operated on with the use of ligature-free suture).

Adult↗

Riboflavin responsive multiple acyl-CoA dehydrogenase deficiency: functional evaluation of recovery after high dose vitamin supplementation.

The effect of riboflavin supplementation on muscle performance and exercise metabolism was investigated in four patients with multiple acyl-coenzyme A dehydrogenase deficiency (MAD). Maximum oxygen consumption and endurance measurements were performed to assess the patients' aerobic capacity and energy metabolism during exercise. They were tested before and after treatment with pharmacological doses of riboflavin. The initially low maximum oxygen consumption and high levels of blood lactate during submaximal exercise suggest that the oxidation of both fatty acids and carbohydrates was severely impaired. All four patients experienced a dramatic improvement in aerobic performance under riboflavin supplementation.

Acyl-CoA Dehydrogenases↗