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Biomedical subjects

S Richmond

Publications and source records attributed to S Richmond.

132 records · Page 8Linked to original sources

Frequent association of chlamydial infection with Reiter's syndrome.

The incidence of infection with Chlamydia trachomatis in 113 men with Reiter's syndrome was investigated. Chlamydiae were isolated from urethral specimens from 40 (39%) of 103 patients and from 36 (69%) of 52 of these men who had signs of urogenital inflammation at the time of examination. Chlamydial antibodies (titers, > or = 8) were detected in sera from 66 (63%) of 104 patients by the complement-fixation test and in sera from 79 (87%) of 91 by a single-antigen indirect immunofluorescence test. Fluorescent chlamydial antibodies were found with equal frequencies in sera from patients whose cultures were negative and sera from patients whose cultures were positive, but the geometric mean titer was higher for the latter group. The results suggest that Reiter's syndrome is frequently associated with cultural and/or serologic evidence of genital infection with C. trachomatis.

Adult↗

[Decreased 67-gallium plasma protein binding in senile dementia of the Alzheimer type].

We examined the plasma-protein-binding of 67-gallium in 10 patients with probable dementia of the Alzheimer-type (DAT), diagnosed according to NINCDS-ADRDA-criteria, and in 10 healthy controls matched for age (mean: 82 and 83 years) and sex (2m:8f). In comparison to the control group, the percentage of 67-gallium bound in the plasma of DAT-patients was significantly decreased (10.6% vs 15.5%; p less than 0.05). As gallium and aluminum show corresponding biochemical characteristics, these results may indicate a potential contribution of a disturbed peripheral transport in DAT, leading to the intracerebral deposition of neurotoxic aluminum levels.

Aged↗