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Biomedical subjects

S Reinis

Publications and source records attributed to S Reinis.

At least 37 records · Page 2Linked to original sources
PubMed1978

Is chemical memory transfer due to shock or behavior training?

A memory transfer experiment was performed to determine whether the transfer effect is due to stress associated with the foot shock or to the specific behavioral training. Recipient animals were significantly better in the 'jump-out' testing than either the shock-control recipients or the control recipients, but the shock-control recipients performed significantly better than the control recipients. Foot shock has an effect on the transfer phenomena but is not responsible for the entire effect.

Animals↗
PubMed1975

Incorporation of (3H)thymidine into brain DNA after cerebellar damage.

Changes of incorporation of [3H] thymidine into brain DNA were studied in C57BL/6J mice after perinatal neocerebellar lesion. The destruction of part of the left neocerebellar cortex caused temporary increase of the specific radioactivity of DNA extracted from neocerebellum (15.22 +/- 0.57 cpm/mg DNA vs. 4.83 +/- 0.40 cpm/mg DNA in controls), from left hemisphere (9.86 +/- 0.45 cpm/mg DNA in operated vs. 4.22 +/- 0.40 cpm/mg DNA in controls), and from right hemisphere (11.75 +/- 0.52 cpm/mg DNA in operated vs. 4.78 +/- 0.39 cpm/mg DNA in controls). The labeled DNA was localized both in glia and in neurons in different brain areas. In animals operated upon in adult age, no changes in labeling of brain DNA were observed.

Animals↗
PubMed1975

Effects of hydroxylamine on the consequences of long-lasting administration of morphine in mice. II. Time course of the hydroxylamine effect on morphine tolerance.

Mice injected for 35 days with morphine sulfate in increasing doses did not show tolerance to the analgesic effects of morphine if injected intracranially with 0.3 M hydroxylamine. The excitatory action of morphine was unaffected. The interference with tolerance lasted for at least six weeks following the hydroxylamine injection. There were no apparent histological changes in the brains of treated mice as well as no differences in the composition of water-soluble brain proteins.

Animals↗
PubMed1975

Effect of hydroxylamine on the consequences of long-lasting administration of morphine in mice. III. Effect on preferred drinking of morphine solution.

C57BL/6J mice were periodically required to drink a morphine solution for one, ten or sixteen weeks and then injected intracranially with the mutagens hydroxylamine or sodium nitrite. Whereas before the injection of the drugs the mice demonstrated a definite preference for morphine, after hydroxylamine this preference disappeared. Sodium nitrite had no such effect on the consumption of morphine solution.

Animals↗
PubMed1975

Effects of hydroxylamine on the consequences of long-lasting administration of morphine in mice. I. Effect on the morphine tolerance.

C57BL/6J mice were injected daily with increasing doses of morphine sulfate for 5 weeks. Twenty-four hours after the final morphine administration, they were injected intracranially with 10, 20 or 50 mul of a 0.3 M solution of hydroxylamine. Two weeks later, hot plate testing indicated that hydroxylamine interfered with the developed tolerance of the mice to morphine.

Animals↗