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Biomedical subjects

S Raman

Publications and source records attributed to S Raman.

At least 145 records · Page 8Linked to original sources

Closed mitral valvotomy in pregnancy--a Malaysian experience.

Our experience from 1968 to 1985 in 12 women requiring closed mitral valvotomy during pregnancy is reviewed. All patients had severe mitral stenosis and were in functional class 3 (2 patients) or class 4 (10 patients). Mitral valvotomy was performed between the 18th and the 30th week of pregnancy using a transventricular dilator. Improvement in functional class was noted in all patients postoperatively. One patient had postvalvotomy mitral regurgitation and heart failure, which responded to diuretics; the subsequent course was uneventful. Eleven patients had normal deliveries; whilst one patient had a Caesarean section for an obstetric indication. All babies were normal and there was no maternal death. This series confirms that closed mitral valvotomy can be performed with an acceptable degree of safety during pregnancy, when indicated.

Abortion, Therapeutic↗

Role of class I and class II HLA antigens in cadaveric renal transplantation.

HLA matching at MT and DQ appears to be an important predictor of allograft survival. Allografts with no MM at MT and DQ have a good outcome while a known MM at MT and DQ appears to be associated with poor allograft outcome. Thus, our priority should be to avoid an MM for these broad-reacting specificities and then to minimize incompatibilities at DR and HLA-B. Furthermore, our data indicate that allografts with MM at DQ and two MMs at HLA-B appear to be at a higher risk. Perhaps these latter transplants should not be performed with conventional immunosuppressive therapy.

Cadaver↗

Intraperitoneal haemorrhage from a ruptured corpus luteum. A cause of "acute abdomen" in women.

During the 10-year period 1974-1983, 68 patients with intraperitoneal haemorrhage as a result of the rupture of a corpus luteum were managed at the University Hospital, Kuala Lumpur, Malaysia. Most of the patients were aged between 18 and 35 years. In 63% of the patients the rupture occurred between the 14th and the 35th day of the menstrual cycle, and 10 patients had intraperitoneal bleeding severe enough (450-1500 mL) to require blood transfusion. The condition is often confused with other surgical emergencies such as appendicitis and ectopic pregnancy. An increased awareness of the problem in women of reproductive age and the use of laparoscopy, when indicated, will allow a more conservative approach to be adopted for those patients with minimal bleeding. The performance of an appendicectomy in the presence of blood in the peritoneal cavity did not appear to increase morbidity in those patients with a preoperative diagnosis of "appendicitis".

Abdomen, Acute↗

Intestinal obstruction following previous myomectomy and the use of beta-sympathomimetics in pregnancy.

Two cases of intestinal obstruction in pregnancy following previous myomectomy are reported. The use of tocolytic agents to suppress premature uterine contractions may be a predisposing factor and probably intensifies the obstruction. As the symptoms mimic the normal side-effects of pregnancy, the diagnosis is often delayed. Laparotomy was done, as initial conservative treatment was unsuccessful in both instances. A live baby was delivered in the first case, whilst the second case ended in an abortion.

Adrenergic beta-Agonists↗