Search PubMed⌕ Search

Biomedical subjects

S R Smith

Publications and source records attributed to S R Smith.

At least 325 records · Page 18Linked to original sources
PubMed1984

Cardiovascular and biochemical responses to nebulised salbutamol in normal subjects.

When conventional therapeutic doses of nebulised salbutamol were given to normal volunteers, there was a significant rise in pulse rate, systolic blood pressure and plasma glucose and a significant fall in diastolic blood pressure and serum potassium in comparison with placebo. Such changes may be potentially hazardous in certain situations. Patients with airways obstruction due to chronic bronchitis who have coexistent ischaemic heart disease or diuretic induced hypokalaemia may be at particular risk from the unwanted cardiovascular and biochemical responses to nebulised salbutamol.

Adult↗
PubMed1984

Coverage: a simulation game to teach health care financing.

Faced with poor student performance on the health care financing questions of a final examination in a community health clerkship, the faculty designed and utilized an innovative simulation game, Coverage, to assist students in learning the complexities of various health insurance plans. This article describes the development, design, and use of this game. Medical students have enjoyed playing the game and have improved their performance in the final examination.

Community Medicine↗
PubMed1983

The effect of faecal loading on colonic anastomotic healing.

The effect of faecal loading of the colon on the healing of rat colonic anastomoses has been investigated in a prospective randomized and controlled study. Anastomotic dehiscence occurred significantly more often when the bowel was loaded with faeces at the time of operation than when it was empty. Suture line cultures bore no relationship to the outcome of the anastomosis. This result emphasizes the importance of an empty colon as a contributory factor in successful colonic healing in the rat.

Animals↗
PubMed1983

Pathologic effects of vaccinia virus on rabbit bone and marrow. An experimental study.

Although viruses have recently been implicated in the pathogenesis of Paget's disease and Perthes' disease, little information is available regarding bone and marrow response to the presence of a noncarcinogenic virus. Vaccinia virus was introduced into the medullary cavity of the femoral shaft of 30 New Zealand White rabbits, and an appropriate control inoculation was performed. Virus was recovered from the inoculation site in 50% of the animals at intervals to one month after inoculation. Histologic abnormalities were observed in 69% of the test femora; similar abnormalities were not observed in the control femora. These abnormalities consisted of bone and marrow necrosis, lymphocyte and plasma cell infiltration, and new bone formation. Some of the newly formed bone was also necrotic. The latter observation suggests an alternative mechanism for the death of new bone, which, in Perthes' disease, has customarily been attributed to repeated ischemic insults.

Animals↗