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Biomedical subjects

S R Porter

Publications and source records attributed to S R Porter.

At least 19 recordsLinked to original sources

Compliance with infection control procedures in a dental hospital clinic.

Dental hospital staff and students were observed during clinical work for their compliance with infection control procedures, as recommended by the British Dental Association. A total of 183 contacts between health care worker and patient were scrutinised during December 1990. Nearly all health care workers (96%) wore gloves to carry out dental treatment, but in some cases gloves were neither changed nor hands washed between patients. Only one half wore protective eyewear and about one third (38%) wore no mask. Some dental surgery assistants used heavy duty gloves and some even scrubbed dirty dental instruments without wearing any gloves. Strict audit is clearly needed in every clinical setting in order to ensure compliance with infection control.

Attitude of Health Personnel

Chronic candidiasis, enamel hypoplasia, and pigmentary anomalies.

This report describes a young male patient who had enamel hypoplasia, persistent oral candidiasis, skin hyperpigmentation, and vitiligo, and was thus suspected of having candidiasis endocrinopathy syndrome. The clinical and laboratory investigations employed to confirm the diagnosis are detailed.

Adolescent

Human papillomavirus type 16 DNA in oral white sponge nevus.

White sponge nevus (WSN) is a benign hereditary lesion of the mucous membranes. DNA extracted from a biopsy specimen of oral WSN was assayed for the presence of DNA sequences homologous to human papillomavirus (HPV) types 1, 2, 4, 6, 11, 13, 16, and 18 by Southern blot hybridization. Only HPV-16 homologous DNA sequences were detected at a copy number of approximately 200 to 250 genome copies per diploid cell. The viral DNA sequences did not appear to be integrated into the host cell chromosome. The finding of HPV-16 in an inherited lesion such as WSN indicates that caution must be exercised in ascribing a causal association in relation to the demonstration of HPV in other mucosal disorders.

DNA, Viral

Linear IgA disease manifesting as recalcitrant desquamative gingivitis.

A case of desquamative gingivitis caused by adult linear IgA disease is presented. Management initially proved to be difficult, however, the introduction of sulfapyridine caused rapid resolution of the gingival problem. This is one of the first reports of desquamative gingivitis caused by linear IgA disease successfully treated with sulfapyridine.

Adult

Immunoglobulin G subclasses in recurrent aphthous stomatitis.

Serum levels of immunoglobulin G (IgG) subclasses were examined in 71 adult patients with minor recurrent aphthous stomatitis (MiRAS). Seven patients (10%) had altered IgG subclasses: six had marginally raised IgG1 levels and one had a low level of IgG3. It is concluded that abnormalities of IgG subclass levels do not underlie MiRAS.

Adult

The risk of transmission of human immunodeficiency virus in dental practice.

After a decade of study of the acquired immunodeficiency syndrome (AIDS) there is evidence to address the concerns of dental staff about possible transmission of human immunodeficiency virus (HIV). This paper reviews that evidence which demonstrates an extremely low risk of transmission of HIV to staff and patients. Only a few isolated cases have implicated transmission during dental practice, however, there are no proven cases where seroconversion has been demonstrated in relation to an exposure during dental treatment.

Dental Staff

Non-A, non-B hepatitis and dentistry: a status report for the American Journal of Dentistry.

The recent identification of one of the causes of non-A, non-B hepatitis (NANBH) has led to an improved understanding of the epidemiology and possible clinical manifestations of this infectious disorder. NANBH is of some concern to dental personnel since the causative agents may be transmitted to health care workers and there is no effective immunization against NANBH. Current recommendations for cross infection control in the dental workplace must apply to NANBH.

Dental Staff

Infection control in dentistry.

The risk of transmission of infection within the dental workplace is low, but recent data have indicated that human immunodeficiency virus transmission between dentist and patient can occur, and that while nosocomial transmission of hepatitis B virus is now less likely, a small but significant number of staff may be at risk of hepatitis C virus and varicella zoster virus infection during dental treatment. Despite these continued risks, shortcomings remain in cross-infection control in the dental workplace. Dental clinicians still fail to take adequate steps to minimize nosocomial infection, inconsistently using appropriate methods of sterilization and not providing ancillary staff with suitable protective clothing. Similarly, although vaccinated against hepatitis B virus, a substantial number of clinicians are reluctant to treat hepatitis B virus- or human immunodeficiency virus-infected patients. Cross-infection control procedures continue to be modified. Of importance, it has been confirmed that protective rubber gloves cannot be reused, as micropunctures develop during rewashing. Sharps injuries are common in dental practice, but there are still no effective measures to prevent postinjury human immunodeficiency virus or hepatitis C virus infection. Instrument sterilization is generally safe and effective, but the contamination of dental unit water supplies remains to be overcome, and while impressions can be placed in disinfectants for up to 1 hour without significant dimensional change, it is not known if infectious agents within the impression material are inactivated by this procedure.

Attitude of Health Personnel

HIV update.

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Acquired Immunodeficiency Syndrome

HIV update.

Explore the source record for details and available documents.

Acquired Immunodeficiency Syndrome

Non-A, non-B hepatitis and dentistry.

Non-A, non-B hepatitis (hepatitis C) is a viral infection(s) transmitted mainly by blood and blood products. Infection is usually asymptomatic, but typically followed by chronic infection, frequently with chronic liver disease. Although probably less than 1% of the UK population (and hence dental patients) are infected, groups at high risk for other blood-borne infections are also at risk for non-A, non-B hepatitis. Immunisation against hepatitis B cannot protect against non-A, non-B hepatitis; recommended cross-infection procedures must suffice to protect patients and staff.

Antibodies, Viral