Influence of pituitary implants in kidney capsule on irradiated murine leukaemia virus (MuLV).
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Biomedical subjects
Publications and source records attributed to S R Pai.
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Arginase activity was found to be increased in precancerous nodules and mammary tumour when compared with the mammary gland. Proline inhibited the mammary tumour arginase and up to 30 mmo1 concentration the inhibition follows first order kinetics. Hill analysis of the inhibition of arginase by proline showed that proline inhibits the arginase activity by competing directly at the active site without conformational change. The inhibition may be of regulatory importanec, involving a feedback mechenism in mammary tumours.
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