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Biomedical subjects

S R Mittal

Publications and source records attributed to S R Mittal.

At least 55 records · Page 3Linked to original sources
PubMed1994

Importance of recording lead V1 in the seventh right intercostal space in diagnosing corpulmonale.

Right-sided chest leads V1 to V6R were recorded in the 4th to 7th intercostal spaces in 25 cases of corpulmonale secondary to chronic obstructive pulmonary disease and in an equal number of age-matched controls. Results were compared with findings in the conventional electrocardiogram. Chest leads recorded in the seventh right intercostal space along the right sternal border could detect 24% of cases of corpulmonale that were missed by conventional leads.

Adult↗
PubMed1994

Isolated right ventricular infarction.

Our experience with 18 cases of isolated right ventricular infarction is reported and the literature is reviewed. Chronic lung disease with right ventricular hypertrophy is an important risk factor. Chest pain is the usual symptom at presentation but some cases can have breathlessness, palpitations or syncope. Some cases can have sinus bradycardia, atrial fibrillation or ventricular tachycardia. Atrioventricular block is rare. Cases with pulmonary artery hypertension, extensive right ventricular infarction due to proximal occlusion of the right coronary artery, right atrial infarction or atrial fibrillation can have hypotension and/or systemic venous congestion. A surface electrocardiogram mainly showing changes in leads conventionally considered to represent left ventricle and right-sided chest leads may not show an infarct pattern in some cases. Echocardiography is, therefore, more reliable in diagnosing this condition. The cautious use of small doses of nitrates and diuretics is not hazardous in the absence of hypotension. High doses of steroids and anti-coagulants can be helpful. The prognosis is usually good, although sudden collapse can occur due to ventricular fibrillation, rupture of the right ventricular free wall or a massive pulmonary embolism.

Adult↗
PubMed1993

Effect of calcium channel blockers on serum levels of thyroid hormones.

One month oral therapy with calcium channel blockers caused significant (P < 0.001) decrease in serum levels of triiodothyronine and thyroxine and significant increase in serum levels of thyroid stimulating hormone in rabbits. Most probable mechanism of action was block in the synthesis and/or release of thyroid hormones.

Animals↗
PubMed1993

Significance of exercise-induced ST-segment deviation in right-sided chest leads in the diagnosis of right ventricular ischemia.

Seventy-three patients were subjected to bicycle ergometry and exercise-induced ST-segment changes in right-sided chest leads were correlated with changes in conventional leads. ST-segment elevation in right-sided chest leads was found to be more frequent than ST-segment depression. ST-segment elevation in right-sided chest leads was commonly reciprocal to ST-segment depression in leads V3 to V7, indicating that this change is usually secondary to left ventricular subendocardial ischemia, rather than to right ventricular ischemia. ST-segment depression in right-sided chest leads was mostly a primary change indicating right ventricular subendocardial or posterior wall ischemia. It is, therefore, felt that ST-segment depression in right-sided chest leads is more sensitive and specific for right ventricular ischemia than ST-segment elevation in these leads.

Adult↗
PubMed1992

Isolated right ventricular infarction.

The literature on isolated right ventricular infarction is reviewed and local experience is reported. Chronic lung disease is an important risk factor. Chest pain and breathlessness are common. Syncope and sudden collapse can also occur. Rhythm disorders include sinus bradycardia, atrial fibrillation and ventricular tachycardia or fibrillation. Atrioventricular block is rare. Hypotension and a right-sided fourth heart sound are common. Cautious use of slow-release nitroglycerin is not hazardous in the absence of hypotension. High doses of steroids and anticoagulants can be helpful. The prognosis is usually good, although sudden collapse can occur due to ventricular fibrillation, rupture of the right ventricular free wall or massive pulmonary embolism.

Adrenal Cortex Hormones↗
PubMed1992

Transvenous pacing in the presence of acute right ventricular infarction.

Ventricular tachycardia and ventricular fibrillation are very frequent during transvenous pacing in the presence of acute right ventricular infarction. An acceptable pacing threshold is not usually achieved. A relatively high pacing threshold should, therefore, be accepted in these cases with minimum catheter manipulation. Invisible or very small pacing spikes, increased time intervals between the spike and paced QRS, atypical QRS configurations and sensing failure are frequent in these cases.

Cardiac Pacing, Artificial↗