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Biomedical subjects

S R Das

Publications and source records attributed to S R Das.

81 records · Page 5Linked to original sources

A longitudinal study of the growth in height of boys and girls of West Bengal (India) aged six months of 20 years.

This study is the first Indian longitudinal growth survey from early childhood to maturity. The heights of 303 boys and 260 girls, from middle-class families in a semi-urban area south of Calcutta, were measured at regular intervals over periods of up to 14 years (between 1952 and 1966). The data were analysed using appropriate mixed longitudinal and curve-fitting techniques. Growth in height of these middle-class Bengali children, who are not a representative sample of the Indian population, is slightly above the national Indian Council of Medical Research Standards. In both sexes, mean heights are below the 10th centile line of the British standards from an early age onwards, mainly due to a smaller prepubertal growth. The adolescent growth spurt in the Indians similar to that seen in British children, as is the age at which it occurs (peak height velocity at 14.0 years in boys, 12.5 years in girls). The sex difference of 14.0 cm in adult stature is attributable to a greater adolescent gain in the boys of 6.0 cm, a greater height in boys at the girls' age at take-off of 3.3 cm and a gain in height by the boys of 4.7 cm between the girls' and boys' ages at take-off.

Adolescent↗

Degree of resemblance of the pattern of growth among sibs in families of West Bengal (India).

The Preece-Baines Model 1 curve has been fitted to longitudinal data on growth in height of 105 boys and girls in 70 Bengal families: 60 of these were sibs distributed in 25 families. For a number of growth characteristics, such as age at peak height velocity, the proportion of the total population variance that was due to variation between, as opposed to within, families was estimated by Smith's (1980) method. The proportions for age at take-off of the adolescent spurt, of age at PHV, and of PHV itself were 22%, 26% and 33% (where adult height gives a value of about 40%). The sample is small and these estimates have high standard errors and need confirmation.

Adolescent↗

A cross-sectional growth study of trunk and limb segments of the Bengali boys of Calcutta.

This report deals with cross-sectional growth of sitting height (SH), subischial length (SL, estimated as height minus sitting height), height of the anterior superior iliac spine (HIS), and total arm length (TAL) of Bengali school boys (Calcutta), aged 7.0-16.0 years. Preece-Baines model 1 (PB1) fits to the cross-sectional means of the four traits estimate the average ages at maximum increment at 12.41 years for SL, at 12.43 years for HIS, at 12.97 for TAL, and at 13.74 years for SH. Maximum increment of the upper and lower segment of the body are reached at an earlier age in the present study than in a longitudinal analysis of semi-urban Bengali boys from the suburban area of Calcutta. Socioeconomic differences and secular trend might explain this shift towards earlier maturation.

Adolescent↗

The effect of erythritol on the stability of gamma-glutamyl transpeptidase and N-acetyl glucosaminidase in human urine.

In toxicology studies and clinical trials of erythritol, treated animals and human subjects had higher urine gamma-glutamyl transpeptidase [gamma-glutamyl transferase (gamma-GT)] than untreated controls. It has previously been reported that gamma-GT activity in frozen urine decreases with time; therefore, a study was undertaken to examine the effects of storage temperature, time, and the presence of erythritol on the stability of gamma-GT and N-acetyl glucosaminidase in human urine. In this study, it was found that the rate of decrease of the activity of gamma-GT is much greater at -20 degrees C than at -70 degrees C. Variation in the storage temperature of the frozen urine is particularly deleterious to gamma-GT. The addition of erythritol in a concentration of 5% reduces this decrease. Approximately 15% of N-acetyl glucosaminidase activity is lost in the initial process of freezing the urine. Thereafter, conditions of temperature, time, and the presence or absence of erythritol account for little additional loss of activity.

Acetylglucosaminidase↗