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Biomedical subjects

S R Cho

Publications and source records attributed to S R Cho.

At least 73 records · Page 4Linked to original sources

Intraperitoneal carcinomatosis: incidence of its radiographic findings and description of a new sign.

Forty documented cases of intraperitoneal carcinomatosis were studied to examine the incidence of common consistently useful radiographic signs. Twenty-four (60%) were radiographically positive. Ten of 19 barium enema examinations (53%) revealed metastatic implant(s) on the colon. This proved to be the most common finding of intraperitoneal carcinomatosis. Other radiographic findings included ascites in 14 patients (35%) and small bowel obstruction in five (13%). A new sign of intraperitoneal carcinomatosis termed "fixed colon" sign is discussed. Seven of 19 cases (37%) with lower GI series demonstrated this sign. Barium enema examination has a high yield in demonstrating intraperitoneal carcinomatosis.

Abdominal Neoplasms↗

Percutaneous unknotting of intravascular catheters and retrieval of catheter fragments.

During a 5-year period, percutaneous unknotting of knotted catheters or retrieval of intravascular catheter fragments was performed in 21 patients by various interventional radiologic techniques. Eight of nine knotted Swan-Ganz catheters were successfully released, whereas one required the assistance of a surgical cutdown under local anesthesia; 10 of 11 embolized catheter fragments in various locations were retrieved successfully. One failure occurred with complication of peripheral embolization in the lung. Four case reports are presented. The overall success rate was 95%.

Adolescent↗

Gastroparesis diabeticorum.

Fifteen patients with gastroparesis diabeticorum were studied retrospectively. The radiographic findings on barium examination of the stomach and small bowel were tabulated and correlated with clinical data. Of these 15 patients, 12 were insulin-dependent. The other three received only oral hypoglycemic agents. Control of the diabetes was poor in seven patients, fair in six, and good in two. There was no correlation between the severity of the radiographic findings and the duration, degree of control, or method of treatment of the disease. Four patients had follow-up studies. Of these, three showed radiographic evidence of improvement or return to normal. The fourth patient showed evidence of gastroparesis unchanged over five years.

Adult↗

Polypoid carcinoma of the esophagus: a distinct radiological and histopathological entity.

The radiological manifestations of four cases of polypoid carcinoma of the esophagus are reviewed. A large pedunculated intraluminal mass, mimicking a foreign body was seen in three of the four cases. Due to this predominant exophytic growth, the follow-up esophagogram was normal in two patients after radiotherapy, despite the very large size of the lesions. The unique histopathology and radiology of this entity are discussed.

Aged↗

Use of isosulfan blue for identification of lymphatic vessels: experimental and clinical evaluation.

Use of vital dyes for identification of lymphatic vessels before cannulation has heretofore not been approved by the Food and Drug Administration (FDA). The suitability of isosulfan blue, the 2,5 disulfonic acid isomer of Patent Blue, for this purpose was evaluated experimentally in the rat and clinically in 11 volunteers and 543 patients under an investigational new drug application. FDA approval for this drug has been obtained. Volunteers and patients received up to 15 mg of a 1% sterile, pyrogen-free solution per extremity (total dose of 0.4 mg/kg in the average patient). Excellent identification of lymphatic vessels was achieved in 100% of volunteers and in 97.4% of patients. In the other 2.6%, lymphatic vessels were not identified mainly due to congenital lymphatic vascular (Milroy) disease. Baseline blood chemistry in volunteers was not altered after administration of the dye. No adverse reactions were found in volunteers and minimal allergic reactions occurred in less than 1% of patients. Acute toxicity studies demonstrated an LD50 greater than 150 mg/kg in the rat. Isosulfan blue was excreted unchanged in the urine (7%) and feces. Comparable excretion was found in volunteers. Isosulfan blue is a safe and efficacious vital dye for lymphangiography.

Adult↗

Carcinoma of the esophagus: assessment of submucosal extent.

Submucosal extension of carcinoma of the esophagus is common, often presenting as a varicoid pattern on the esophagogram. Forty-two per cent of our 153 patients with carcinoma of the esophagus showed area(s) of a varicoid pattern in association with the other usual pattern(s) (fungating, ulcerating or infiltrating). A few of the patients have findings similar to those associated with esophageal varices on the esophagogram. Such patients are identical to those with "varicoid carcinoma" reported in the literature. The differentiation between varicoid carcinoma dn esophageal varices may be made on fluoroscopy, where the former is characterized by rigidity and the latter by flexibility.

Aged↗

Esophageal intramural pseudodiverticulosis.

Esophageal intramural pseudodiverticulosis (EIP) is a rare condition of unknown etiology. It is characterized by multiple, small, flaskshaped outpouchings in the esophageal wall. Involvement may be segmental or diffuse. Since this entity was first reported in 1960, there have been 43 cases described in the English literature. These cases are reviewed and six additional cases are reported with emphasis on clinical and radiographic parameters of this entity.

Adult↗

Pulmonary arteriography in patients with hilar or mediastinal masses and lung scans suggesting pulmonary embolism.

Three patients with clinical features of pulmonary embolism were evaluated by chest roentgenograms, perfusion lung scanning, and pulmonary arteriography. All of them had hilar and/or mediastinal masses which were obvious in one patient, subtle in another, and not discernible in the third. The three patients had abnormalities on lung scans, including unilateral absence of perfusion in two and lobar absence of perfusion in one. The extent of the perfusion defects correlated poorly with the roentgenographically visible masses. Pulmonary arteriograms were abnormal but none showed evidence of pulmonary embolism. Lung scanning is often unreliable in establishing the diagnosis of pulmonary embolism in patients with hilar or mediastinal masses. Pulmonary arteriography may demonstrate the mass if it is vascular, or may show extrinsic compression upon the pulmonary vasculature. Lung scanning may be of value in localizing a mass not visible on chest roentgenogram in a patient suspected of harboring a bronchogenic carcinoma.

Adult↗

Round (helical) atelectasis.

Round (helical) atelectasis is a little-known form of pulmonary collapse. It is thought to occur secondary to lung compression from pleural effusion or following therapeutic pneumothorax. Its occurrence is favoured in patients with exudative pleural effusions and extensive pleural thickening. It presents radiographically as a pulmonary pseudotumour, and experience with this entity and its pathogenesis are discussed.

Humans↗