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Biomedical subjects

S R Brown

Publications and source records attributed to S R Brown.

At least 73 records · Page 4Linked to original sources
PubMed1984

Clinical aspects of experimentally induced chloride deficiency in Holstein calves.

A severe total body chloride deficit was induced in Holstein calves by feeding a low-chloride ration (0.063% Cl) and removing digesta daily from the abomasum through a surgically implanted cannula. Clinical signs of the deficit observed included polydipsia, polyuria, dehydration, anorexia, scleral injection, decreased respiratory rate, and blood and mucus in the feces. Necropsy findings included dehydration, blood in the lumen of the small intestine, and renal lesions. The most extensive histopathologic changes occurred in the renal tubular epithelium of the outer medulla where mineralization of the tubular epithelium and basement membranes was frequently seen.

Animals↗
PubMed1983

Systemic and renal effects of angiotensin II in the freshwater turtle Pseudemys scripta elegans.

This study examined the renal and systemic effects of angiotensin II (ANG II) in the freshwater turtle, Pseudemys scripta elegans. We infused [Asn1, Val5]ANG II at doses of 1, 10, 100, and 500 ng X kg-1 X min-1 in conscious turtles while monitoring blood pressure, glomerular filtration rate (GFR), urine volume, and plasma and urine electrolytes. Saline (0.6%) was infused for two 1-h control periods at 1 ml X kg-1 X h-1 followed by a 1-h infusion of saline with ANG II added. Saline alone was then infused for either two or three 1-h recovery periods. Control values before ANG II infusion averaged 21 mmHg for blood pressure, 1.8 ml X h-1 for urine volume, and 8.0 ml X kg-1 X h-1 for GFR. At 1 (n = 7) and 10 ng X kg-1 X min-1 (n = 6) ANG II produced no significant changes in blood pressure or renal function. Angiotensin infusion at the higher rates of 100 (n = 6) and 500 ng X kg-1 X min-1 (n = 11) significantly elevated blood pressure during ANG II infusion (29 and 44 mmHg, respectively), while electrolyte excretion remained unchanged. Despite the increased blood pressure, GFR and urine volume tended to decrease. At all infusion rates, plasma electrolytes remained unchanged. The results suggest that ANG II is a potent constrictor of preglomerular vessels in the kidney of the turtle.

Angiotensin II↗
PubMed1977

Feldenkrais versus conventional exercises for the elderly.

Tenants in retirement housing given a 6-week program of Feldenkrais exercises were compared with a group given conventional exercises and with control groups given no exercises. Analysis of covariance of preliminary and subsequent measurements failed to yield any significant differences between groups. Measurements included height, weight, blood pressure, heart rate, balance, flexibility, morale, self-perceived health status and level of performance of activities of daily living, also the number of body parts difficult to move or giving rise to pain. Several possible reasons are given for the results. Attention is drawn to the necessity of medically screening and monitoring elderly registrants for exercise programs since it is apparent that some sign up who should not.

Activities of Daily Living↗