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Biomedical subjects

S Punsar

Publications and source records attributed to S Punsar.

At least 55 records · Page 3Linked to original sources

Mortality and incidence of chest pain after an exercise intervention programme.

One hundred and sixty-six middle-aged Finnish men free of clinical coronary heart disease (CHD), but having at least one CHD risk factor, participated in an 18-month controlled exercise intervention study, one-half as an exercising group and the other half as a matched control group; thereafter all 166 followed a partially controlled exercise programme for the next year. These men formed the intervention group for the present follow-up study covering the subsequent 6 years. The reference group for the follow-up comprised 152 men who fulfilled the same inclusion criteria for the original study as the intervention subjects, but who had been excluded from the study for non-medical reasons, mainly because they could not be pair-matched. Mortality statistics were collected, and a postal questionnaire on chest pain symptoms and physical activity was sent to all of the men 8 years after the start of the study. On CHD death and four deaths occurred in the reference group, and one CHD and no other deaths in the intervention group. Severe chest pain possibly suggestive of myocardial infarction was more common in the reference group than in the intervention group, but no difference was found in angina pectoris symptoms. The level of recent physical activity or smoking did not affect the chest pain symptoms independently.

Adult↗

Drinking water quality and sudden death: observations from West and East Finland.

Relationships of drinking water quality to CHD and sudden death were studied in two rural areas in western and eastern Finland. In the eastern area, drinking water is particularly soft and contains less magnesium and chromium but more copper than in the western area. A 15-year follow-up of resident males showed a higher death rate from CHD in the eastern area but no difference in the proportion of sudden deaths. The data suggest that CHD may be associated with low concentrations of magnesium and chromium in the drinking water, but no definite relationship was found between water quality and sudden death.

Chromium↗

Smoking, carbon monoxide, and atherosclerotic diseases.

Smoking habits and random measurements of the proportion of haemoglobin bound to carbon monoxide (COHb%) were examined for their association with atherosclerotic diseases in 1068 men aged 55 to 74 years from rural areas of Finland. COHb% and smoking history were similarly associated with claudication and coronary heart disease. Random measurements of COHb% did not show a better overall relation to the prevalence of atherosclerotic diseases than smoking history, though COHb% showed a stronger association with a probable previous myocardial infarction. Further studies are needed to clarify the role of carbon monoxide in atherosclerosis.

Aged↗

Electrocardiographic low-frequency QRS notching and ventilatory impairment in patients with pulmonary tuberculosis.

The occurrence of notching in the initial and terminal parts of the QRS complex of the ECG was studied in a series of 1072 patients with active or healed pulmonary tuberculosis. Terminal notchings were associated with ventilatory impairment: in the male group the percentage of patients with terminal notching increased from 5 to 20% as the FEV1.0% decreased from larger than or equal to 80 to below 40. Initial notchings were not associated with ventilatory impairment. The relationships were similar when studied separately in groups with and without left heart disease.

Electrocardiography↗

Urinary chromium excretion and atherosclerotic manifestations in two Finnish male populations.

The urinary exretion of chromium was studied for relationships to atherosclerotic diseases in two rural Finnish male populations, aged 55 to 74; one from eastern Finland, the other from the southwestern part of the country. A 10-year follow-up had shown a particularly high mortality from coronary heart disease in the eastern area where the concentrations of chromium in the drinking water were lower than in the western area. The 24-hr urinary excretions of chromium of the two populations were markedly low (east, mean +/- SEM, 3.60 +/- 0.15 microgram; west, 3.74 +/- 0.13 microgram), suggesting a suboptimal chromium intake in both populations. No consistent differences were found in urinary chromium excretions between groups with atherosclerotic diseases and reference groups. The role of low chromium intake in the pathogenesis of atherosclerosis deserves further study.

Aged↗