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Biomedical subjects

S Prigouris

Publications and source records attributed to S Prigouris.

3 recordsLinked to original sources

Experimental autotransplantation of the parathyroid gland.

The lateral parathyroid gland of the rabbit was resected and autotransplanted under an ear skin flap. A skin flap at the opposite side was used as control. The success of autotransplantation was established by microangiography of the transplant and by measuring plasma concentrations of parathyroid hormone (PTH), calcium and phosphorus. After 4 months the animals were killed and the transplant was studied histologically and by electron microscopy. Fourteen animals were included in the study. There was an increase in PTH derived from the transplanted gland after 4-6 postoperative days. All animals developed hypocalcaemia during the 3 days after transplantation. There were no significant changes in serum phosphorus. Transplantation did not alter the morphology of the distribution of the cells in the transplanted gland, which functioned normally after the fourth postoperative day.

Animals↗

Toxic megacolon secondary to acute ischemic colitis.

A 72-year-old woman without significant medical history was admitted with abdominal pain, high fever, leukocytosis, bloody diarrhea and marked dilation of the transverse, descending and sigmoid colon. Toxic megacolon was diagnosed and responded well to medical treatment. Seven weeks after her admission, however, the patient developed a stenotic lesion in the sigmoid colon. The lesion was managed surgically. Histological examination of the resected colon revealed resolving ischemic colitis affecting only part of the thickness of the intestinal wall. The patient has been healthy since the surgery, i.e., for two years.

Acute Disease↗

Duodenostomy.

The methods of managing a difficult duodenal stump after gastric resection are reviewed. One of two methods of catheter drainage of the duodenum can be used: end-stump catheterization or lateral tube drainage. A series of cases managed by end-stump duodenostomy is reviewed. The rationale for this technique and its advantages are presented.

Drainage↗