Cerebriform tongue-a clinical sign in pemphigus vegetans.
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Biomedical subjects
Publications and source records attributed to S Premalatha.
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Tylosis at birth was found as an autosomal dominant inheritance in twenty-two members of a family spanning over five generations. Of those affected three of the fourth generation tylotics developed squamous carcinoma of the tylotic skin and one of these died of carcinoma of the oesophagus. It is possible that there is a genetic association between the state of the oesophagus and the tylosis of the palms and soles which predisposes both sites towards the development of squamous carcinoma.
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The occurrence of pyogenic granuloma following nose-boring for the wearing of ornaments is recorded. Boring of the nose is seen in 60--70% of women in our skin out-patient department and pyogenic granuloma occurs in 33% of such women. The condition is not encountered after boring of the ear lobes, and this suggests that the tissues of the alae nasi are abnormally susceptible to this reaction.
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A case of tylosis following corrosive stricture of the oesophagus in a male of 26 years is recorded. It is suggested that there is probably a connection between the state of the oesophagus and the state of palms and soles and that an oesophageal abnormality may precede tylosis of the late onset type.
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