Biomedical subjects
Publications and source records attributed to S Pons.
We presented a patient with a deforming and necrotizing syndrome of the nasal pyramid. The histopathology demonstrated a lymphoma. The original works of Weiss are related. The diseases is characterized by: ecotaxis of the nasal pyramid, localized persistency during a long time, malaise in advanced studies and sensibility to radiations. We proposed the name linfoma histiocitico maligno nasal de Weiss and consider it as a autonomous entity.
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Under the name of Duhring-like Polymorphous Dermatitis are grouped skin diseases with the following common patterns: clinical manifestations, course and treatment. Surely are from immunological etiopathogenesis. They should be studied with microscopy and immunofluorescence.
Three cases of Bullosis Diabeticorum, entity described by Rocca and Pereyra, are reported by the authors. The review of the published literature after the original article shows the importance of recognizing these symptoms for the diagnosis of an occult diabetes. The most outstanding features of the studied cases were: a) the bullosis traumatica present in the 3 observations; b) the finding of an unknown diabetes in two of the three patients; c) the association with stellate pseudoscars. The histopathologic findings were similar in all three patients.
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Two cases of naevus lipomatosus superficialis (Hoffmann and Zurhelle) are described by the authors. The main clinical characteristics and histological peculiarities are reviewed. Both cases were disseminated and had typical localisation (pelvic area). The histological examination showed ectopic adipocytes in the dermis. The authors mare a reference to the different hypotheses on the pathogenesis of these lesions.
A bibliographic review of a new subject-pemphigus with eosinophilic spongiosis accomplished: Three clinical courses are recognized: a) pemphigus in its initial phase, b) pemphigus markedly seborrheic, which presents during its evolution, some morphologic anomalies, c) pemphigus that appear like an authentic Duhring in its initial phase and during part of its evolution. On studying the histopathology three aspects are observed; 1) pure eosinophilic spongiosis with two modalites: diffuse or vesiculate; 2) mixed eosinophilic spongiosis and, 3) alternate eosinophilic spongiosis. The review report the study of this new observation and discusses the nosological situation as well as its pausible causation.
After describing the affections caused by the virus Coxsackie, the characteristics of disease in mouth-hands-feet are looked over reporting the principal epidemic outbreak as well as the isolated forms of exhibition. The illness can be shown in a complete, incomplete or moderate way. This outbreak occurred in Mendoza (Argentina) in 1975-1976: 25 school aged children were controlled and no other relatives of different ages fell ill. No predisposition for either sex. They didn't come from the same school. A sudden eclosion and without general display. In some of them the buccal were absent. All of them had palm and sole lesions and only four of them had buttock lesions. Everybody recovered after a short eruptive period and without any complications.
3 cases of cocidiomycosis observed in the province of Mendoza (Argentina) are described by the authors. The study of the endemic cocidiomycosis in Argentina and the ecological aspects of this disease in Mendoza are studied by the authors.
Bibliographic review of all the published cases of granuloma gluteale infantum and study of the second observation in Argentina. In this case there was a previous Leiner's erythrodermia treated with fluorinatec corticoid creams. The typical lesions appeared suddenly. The authors made a histopathologic study and a review of the pathogenetic theories on this dermatose. In the observation of authors the lesion disappeared in spite of persistence with the treatment with fluorinated corticoid creams, one of the causes of this dermatose according to some authors.
The molecular weights and the integrity of the two major components of ribosomal RNA from a wide variety of eukaryotic species, from protozoa to man, has been investigated by polyacrylamide gel electrophoresis under fully denaturing conditions. The results show that the s-rRNA is largely heterogeneous, ranging in size, from 0.65 X 10(6) to 0.96 X 10(6) dalton. The l-rRNA ranges in size from a minimum mol wt of 1.28 X 10(6) to a maximum weight of 1.60--1.66 X 10(6) (of warm-blooded vertebrates, Cephalopoda and Diptera); several intermediate values have been found in lower organisms and Protozoa. The s-rRNA is a truly continous, uninterrupted polynucleotide chain in all groups of organisms (protozoans, plants, fungi and animals). The larger rRNA is a continous un-nicked chain in all of the deuterostomian animals, plants and fungi. However, the l-rRNA of all the protostomian animals and the protozoa is an aggregate molecule consisting of two subunits held together by limited regions of hydrogen bounding; in these organisms the size of the s-rRNA is generally identical to that of the larger fragment of the l-rRNA. Analysis of the molecular weights of the subunits of the l-rRNA in the protostomians and the protozoa suggests that the l-rRNA contains one short stretch, prone to nucleolytic attack, dividing the RNA chain into a molecularly conserved portion (0.65 to 0.72 X 10(6) dalton) and a variable portion (0.65 to 0.96 X 10(6) dalton).
Clinical study and bibliographic review of the lymphomatoid papulosis (Macaulay-1968) and parapsoriasis varioliformis acute (Mucha-1916). A personal case is reported after a review of nosological location of these diseases and the variable prognosis. The authors reach the following conclusions: 1st) From the clinical point of view the small number of lesions in the lymphomatoid papulosis bring about a different clinical picture from that of parapsoriasis varioliformis acuta in here usually there is a considerable number of lesions. 2nd) There are concomitant lesions of parapsoriasis gutata in parapsoriasis varioliformis and none of the type in lymphomatoid papulosis. 3rd) Protracted course in lymphomatoid papulosis and short lived eruption in the parapsoriasis varioliformis acuta. 4th) From the histological point of view denser and atypical infiltrate in cases of parapsoriasis varioliformis.
A new case of hereditary acrokeratotic poikiloderma of Weary is presented by the authors. There was no eczematoid dermatitis and the patient was the only member of the family affected. There were similarities with the cases published by Piñol Aguadé and co-workers. The authors suggest that this disease can appear in two forms; a complete form (Weary type) and an incomplete form (Piñol type). The histology of the keratotic lesions is reported for the first time. The lesions are very similar in the 15 cases published up to 1975, and the authors believe that it constitutes a well defined entity.
A case of true mielinic neuroma is described. An exhaustive review of the literature on this subject, basically of the Bolande article is carried out by the authors. The mielinic neuromata are a partial aspect of the complexe neuro-crestopathic syndromes associating the cutaneous lesions to: 1) Medullary tyroid carcinoma, 2) pheocromocytoma and 3) neurofibromatous lesions. The observation related by the authors shows: 1) Ehlers-Danlos disease (not described previously), 2) skeletal abnormalities, 3) medullary tyroid carcinoma and 4) pheochromocytoma symptoms.
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