Pyoderma gangrenosum: successful treatment with minocycline.
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Adult↗
Biomedical subjects
S Piper
Publications and source records attributed to S Piper.
Bone abnormalities in the Cape Vulture (Gyps coprotheres).
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Animals↗
Enhanced delayed hypersensitivity skin test reactivity with serial testing in healthy volunteers.
Delayed hypersensitivity skin testing with multiple antigens is frequently used to evaluate immunopotentiation therapy in man. Since serial skin testing with a single antigen has been shown to augment the skin test response, the present study was undertaken to assess the effect of serial delayed hypersensitivity skin testing on skin test reactivity with multiple antigens. Each of twelve healthy volunteers received 0.1 ml of five antigens on two occassion, 6 weeks apart. The antigens used were streptokinase-streptodornase, Candida, Trichophyton, mumps and Mycobacterium tuberculosis (PPD). The results demonstrated enhancement of skin test reactivity in the majority of tests. Indeed, 38.9% of the tests which were negative with the first skin test ( less than 10 mm induration) converted to positive. Enhancement in reactivity was observed in the majority of test subjects with all antigens except PPD. Similar enhanced skin test reactivity was observed in fifteen additional subjects tested serially with Candida only. The observations in this study suggest that uncontrolled studies of immunopotentiation must be interpreted with caution since serial delayed hypersensitivity skin testing with single or multiple antigens results in enhanced skin test reactivity.
Adult↗
Selective involvement of the first carpometacarpal joint in scleroderma.
Selective involvement of the first carpometacarpal joint is described in four women with scleroderma. Radiographic abnormalities at this site included osseous erosion, radial subluxation of the metacarpal base, and (in two patients) intraarticular calcification. Perlarticular osseous erosions were noted at adjacent locations in three patients. The cause of this distinctive wrist finding in scleroderma is unknown, but its similarity to alterations in other connective tissue diseases suggests that muscular and tendon imbalance may be important in producing bone erosion and subluxation at this articulation.
Aged↗
Development and initiation of a diabetes self-management program for an underserved population.
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Ambulatory Care Facilities↗
1996 International Emerging Leaders. Smart, compassionate, committed. A quartet of young leaders honored by The Healthcare Forum and Korn/Ferry International.
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Administrative Personnel↗
Reorganizing without agonizing.
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Communication↗