Biomedical subjects

S Piepenbrock

Publications and source records attributed to S Piepenbrock.

At least 163 records · Page 9Linked to original sources

PubMed1977

[Monitoring of cardio-pulmonary parameters in cases of severe multiple injuries (author's transl)].

Haemodynamic parameters were monitored for one week (in greatest detail during the first 24 hours) in 35 severely injured persons who had been admitted for treatment within one hour after the accident and, as judged by the type of injury, had probably lost more than 1 1/2 litres of blood. The estimations included not only blood pressure, heart rate and shock index; but the cardiac index, pulmonary arterial pressure, pulmonary capillary pressure and parameters of oxygen transport were also determined with the aid of Swan-Ganz catheters. The importance of the data as guide-lines for the correct type of intensive therapy and their prognostic significance are discussed. The evidence provided by the cardiac index, pulmonary arterial and capillary pressure and the parameters of oxygen transport are of particular importance in these cases. A list is added of the values of some haemodynamic factors which should be taken into account in the initial treatment of severely injured persons.

Accidents, Traffic↗

PubMed1977

[Cardiovascular parameters following severe multiple injuries].

Cardiovascular parameters of 35 patients with multiple injuries are monitored over a period of 7 days. Pulmonary artery pressure, pulmonary vascular resistance, intrapulmonary shunts and cardiac output appear to have a significant prognostic value.

Adolescent↗

PubMed1977

[Combination of etomidate and fentanyl. Haemodynamics, inotropic state, myocardial oxygen consumption, and vascular reactions (author's transl)].

The influence of a combination of fentanyl (0.1 mg) and etomidate (0,15 mg/kg and 0.3 mg/kg) on haemodynamics, inotropic state, myocardial oxygen consumption and vascular reaction has been investigated in 60 patients with congenital or acquired heart diseases--mostly functional class III according to NYHAC. Because of minor changes in haemodynamics (decrease in mean arterial pressure, left ventricular pressure, peak dp/dt, cardiac index, stroke index) the combination of 0.15 mg/kg etomidate and 0.1 mg fentanyl seems to be of great value for induction of anaesthesia in patients with cardiac disease compared to other intravenous induction agents such as propanidid, thiopentone or althesin. In accordance with the changes in haemodynamics there was a 12% and 18% decrease in myocardial oxygen consumption, respectively.

Alfaxalone Alfadolone Mixture↗

PubMed1977

[Cardiac and selective vascular effects of canrenoate-potassium (aldactone pro injectione) in cardiosurgical patients (author's transl)].

Hemodynamic and inotropic effects of 200 mg and 400 mg Aldactone pro injectione (Canrenoate-Potassium, Aldadiene) were measured in three different series (n=60) during and after cardiac surgery in neuroleptanalgesia; results were compared to a control group (n=35). The first investigation was performed after sternotomy and pericardiotomy. During a measuring period of ten minutes no significant changes in inotropic parameter dp/dt max were found in comparison to individual control values. The second investigation during "steady state" extracorporeal circulation revealed a small decrease in arterial perfusion perfusion pressure after both dosages, which can be interpreted as an arteriolar vasodilatation. There was, however, no significant difference in comparison to the control group. Additional measurements were done after cardiac surgery in a total of 20 patients (200 mg and 400 mg Aldactone pro injectione) during an investigation period of 60 min. In comparison to a control group (n=15) no significant differences in arterial pressure, heart rate, cardiac index, stroke index and pulmonary arterial pressure were found. There were no acute and direct positive inotropic effects of Canrenoate-Potassium after administration of 200 mg and 400 mg respectively in cardiosurgical patients.

Adolescent↗

PubMed1976