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Biomedical subjects

S Philippou

Publications and source records attributed to S Philippou.

45 records · Page 3Linked to original sources

Hemangiopericytoma of the head and neck region. A clinical and morphological study of three cases.

Whereas the morphological picture allows classification of malignant hemangiopericytomas with great accuracy, classification of hemangiopericytomas exhibiting a histologically and cytologically benign picture can be difficult. Three hemangiopericytomas of the head could be studied in detail both clinically and morphologically. Inspite of light, scanning and transmission electron microscopic, immunohistochemical and electron microscopic studies no reliable histological criteria indicative of the biological pattern of so-called "benign" hemangiopericytoma could be found. Thus, it appears appropriate to consider all hemangiopericytomas as potentially malignant.

Actin Cytoskeleton↗

[Pulmonary fibrosis after inhalation of amorphous silicic acid].

Light- and scanning electron microscopical studies with energy dispersive x-ray microanalysis were performed on biopsy material obtained from two patients with longstanding occupational exposure to amorphous silica, in whom radiologically interstitial pulmonary fibrosis in vicinity of dust deposits, which could be identified as amorphous and rarely as crystalline silica, was found. The direct topographical relationship between the dust deposits and the tissue reaction indicate that the amorphous silica incorporated in the fibrotic foci is responsible for the development of the fibrosis.

Adult↗

Scanning electron microscopic studies and x-ray microanalysis of hyaline bodies in odontogenic cysts.

70 odontogenic cysts with hyaline bodies (HB) were examined by light and scanning electron microscopy. The scanning electron microscopic studies were performed on dried tissue material, which had been previously examined by light microscopy and energy dispersive x-ray analysis of the histologic sections. The form and basic structure of both the early forms of HB as well as the HB Type I and II could be identified more closely. The early forms, the outer component of the HB Type II and the inner and outer component of the HB Type I consisted of a fine-grained substance, which presumably goes through varying "partial homogenization", thus giving the HB an increased firmness and elasticity. The HB are a product of the epithelium of odontogenic cysts and have direct contact to the outer layer of the adjacent cyst epithelium via its intercellular bridges.

Calcium↗

[Roentgen microanalysis of dust particles in histologic sections of pneumoconiosis].

We investigated the significance of X-ray element analysis of histological sections obtained from 26 patients with pneumoconiosis (occupations, etc. mining, quartz processing, metal polishing, exposure to aluminium dust, exposure to asbestos dust). Aluminium-containing or, in the case of asbestosis, magnesium-containing silicates were the most commonly found minerals. Iron and titanium were detected in particular in the sections obtained from metal polishers. X-ray micro-analysis permits a more accurate determination of dust exposure, and an improvement in the description of the pneumoconiosis presenting.

Asbestosis↗

[Pneumonia following bronchography].

The extravasation of contrast medium into the alveoli during or following bronchography would appear to be associated with an increased complication rate. The histomorphological changes occurRing may vary in degree, and it may thus be difficult to differentiate such changes from those associated with other forms of pneumonia and pneumoconiosis. This paper reports on a case in which, using energy-dispersive X-ray micro-analysis in the scanning electron microscope, the presence of contrast medium within a region of alveolar pneumonia was observed, thus enabling accurate establishment of the cause of this condition.

Adult↗

[Histogenesis of hyaline bodies in odontogenic cysts].

66 odontogenic cysts containing hyaline bodies were studied under the light microscope, in immunohistochemical assays and by SEM using energy dispersive radiomicroanalysis. Part of the hyaline bodies consists of two components. The external hyaline component, which we consider as a specific product of the odontogenic cyst epithelium, consistently contains the elements calcium and phosphate. The internal component, if present, is either of an exogenous (foreign body) or an endogenous nature. It was possible to define precursors of hyaline bodies and to attribute them to the individual types of hyaline bodies.

Hyalin↗