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Biomedical subjects

S Perneczki

Publications and source records attributed to S Perneczki.

3 recordsLinked to original sources

[Comparison of solid phase and liquid-liquid extraction of diazepam and nitrazepam].

We have developed a new extraction technique for nitrazepam and diazepam using Samplex C-18 column. The blood-extractions containing diazepam and nitrazepam were diluted with acetonitrile-water 7:3 eluent. Diazepam and nitrazepam were isolated using liquid-liquid extraction technique. The blood-extracts were diluted with chloroform-ethanol 1:1 and they were evaluated by using OPLC method. Evaluation was done by TLC-scanner (Shimadzu). The efficiency and sensitivity of the methods have been compared.

Chromatography

[Postmortem studies on Prodectin].

Author described a new method for the postmortem investigation of the active component of a new medicament Prodectin. For the extraction of it from the organs acetic-alcoholic methode was used. Isolation and quantitative determination of the subtance was carried out by layer-chromatography, quantitative determination by UV-sectrophotometry. The distribution of the substance in organs was also investigated.

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