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Biomedical subjects

S Palla

Publications and source records attributed to S Palla.

At least 55 records · Page 3Linked to original sources
PubMed1989

A rational postoperative follow-up with carcinoembryonic antigen, tissue polypeptide antigen, and urinary hydroxyproline in breast cancer patients.

Breast cancer patients (n = 224) aged 28 to 81 were postoperatively followed up with serial determinations of carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), and urinary hydroxyproline (OHP). The clinical usefulness of these tumor markers to diagnose and monitor distant metastases was compared with that of the imaging techniques commonly used to monitor breast cancer patients (bone scanning [BS], liver echography [LE], chest radiograph, and skeletal radiograph). So far, 23 patients withdrew from the study, and distant metastases occurred in 33 patients. In 91% of the metastatic patients, constant elevation or progressive increase in serum CEA and/or TPA levels were the first pathologic findings of the relapse. Of the remaining 168 nonrelapsed patients, 122 were followed up longer than 24 months (43 +/- 17 months; mean +/- SD). In these 122 patients the false-positive results of CEA, TPA, and OHP were 0.8%, 2.4%, and 0%, respectively, when used simultaneously with clinical examination and the common laboratory examinations. BS and LE are the only imaging techniques that showed such a high sensitivity to be suitable in the postoperative follow-up of breast cancer patients. Nevertheless, because BS has a low specificity and is not harmless, it should be performed at longer intervals than tumor markers. Eventually, in the relapsed patients, TPA and OHP well reflected the response to treatment better than CEA and prevented useless radiologic examinations.

Adult↗
PubMed1987

[Computerized tomography in the diagnosis of abscesses of the posterior pararenal space secondary to surgical interventions on the abdomen].

The authors analyse the possibilities offered by CT in the diagnosis of the abscesses of the posterior pararenal space (secondary to surgical operation) relating 10 cases observed. The features described by many authors in the latest literature are compared with those observed in the cases reported, showing the real diagnostic sensibility of CT in these situations of relative urgency. The panoramic image offered by CT is particularly useful in the "blind " examinations and in exactly directing the surgical approach or, in alternative, the echo-guided percutaneous puncture of the abscess.

Abdomen↗