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Biomedical subjects

S P Mironov

Publications and source records attributed to S P Mironov.

At least 19 recordsLinked to original sources
PubMed1994

[The use of myolastan in athletes with myoenthetic injuries].

Myolastan was given to 9 sportsmen with acute muscular injury and 5 with chronic one in addition to the standard treatment. Control subjects with similar acute and chronic injuries (7 and 3 patients, respectively) were not given the drug. The patients with acute injuries on myolastan resumed muscular exercise 4.5 weeks after the trauma, while similar controls were able to do that only 6 weeks after it. Chronic injury patients returned to their routine loads 1 week earlier than controls. Myolastan proved effective in combined treatment of acute and chronic myoenthetic damage.

Acute Disease↗
PubMed1991

[Functional condition of the liver after surgical treatment of cirrhosis in children as revealed by hepatoscintigraphy].

Scintigraphy with colloid 99mTc (56 cases) and the radiopharmaceutical preparation 99mTc--HIDA (43 cases) was performed in children with early and developed cirrhosis of the liver to study the functional condition of the hepatic Kupffer's and parenchymal cells in the long-term periods after surgical treatment. Increased activity of the parenchymal cells and inactivation of Kupffer's cells were revealed after splenectomy. The formation of a portocaval shunt and denervation of the hepatic artery promoted activation of hepatocyte functioning in these patients.

Child↗
PubMed1991

[A 99mTc-colloid study of the intrahepatic blood flow in liver cirrhosis in children].

Hepatoscintigraphic investigations were conducted in 63 patients aged 3 to 15 to study the features of intrahepatic blood flow and degrees of its compensation in children with liver cirrhosis of different stages. 99mTc-colloid was employed as a radiopharmaceutical. Disproportions of scintigraphic liver images showed close correlation with clinico-biochemical and morphological signs of the severity of disease. Subcompensation and decompensation of the organ blood flow and reticuloendothelial system in children with developed and terminal stages of liver cirrhosis are characterized by prolonged blood RP inhibition, a decrease in the total clearance of radioactive colloid, a progressively reduced index of liver clearance, and an increase in a colloid uptake by the spleen.

Adolescent↗
PubMed1989

[Determination of the functioning volume of the liver by multipositional scintigraphy and emission-computed tomography].

The paper is concerned with methods for the determination of the liver volume using polypositional scintigraphy (PS) and computed emission tomography (SPECT). The accuracy of both methods was assessed using a liver phantom. The methods were tested in clinical practice on patients with diffuse liver lesions. A liver volume value compared with values in normometric tables as well as differences between a geometrical volume calculated by PS and a volume calculated by SPECT were of diagnostic importance.

Adult↗
PubMed1989

[Stress fractures of the metatarsal bone in sportsmen (Jones' fracture)].

The authors examine the peculiarities of the diagnosis, the clinical course and the roentgenologic manifestations of the fracture of the 5th metatarsal bone, the so-called Jones' fracture, in sportsmen. In this type of injury a good treatment result, i.e. the consolidation of the bone and the recovery of the foot at the early posttraumatic period is achieved by surgical treatment which provides for a necessary compression at the fracture site.

Adolescent↗
PubMed1989

[Evaluation of the activity of liver and spleen macrophages in children with hepatitis A and B].

To form a judgement about function of liver and spleen macrophages (MP) in vivo, use was made of dynamic scintigraphy with Tc-colloid. Sixty-seven children aged 5 to 14 years were examined. Of these, 45 children were afflicted with virus hepatitis B (VHB), 16 with virus hepatitis A (VHA), and 6 children had VHA associated with asymptomatic HBsAg carriership. There was an appreciable decrease of the activity of liver MP attended by consistent compensatory activation of spleen MP in all the etiological types of virus hepatitis. The changes seen in patients with VHA and VHB turned out similar, differing in the rate of the recovery of normal correlations, which was more rapid in VHA. The characteristic feature of liver and spleen MP function in patients with VHA associated with HBsAg carriership consisted in the lack of the compensatory reaction on the part of spleen MP, which was likely to be connected with overstrain of long standing and depletion of the MP system due to permanent antigenic stimulation of HBsAg. The relationship was disclosed between the activity of organ MP and the phase of the infectious process, its gravity and course as well as the character of the patient's premorbid status and intercurrent infection.

Adolescent↗
PubMed1988

[Hemodynamic and functional changes in the liver of children with extrahepatic portal hypertension in relation to the method of portacaval shunt].

Scintihepatographic investigations with colloid 99mTc before and after operations in 4 groups of children were performed: with cavo- or ileomesenterial anastomosis, with splenorenal anastomosis with splenectomy and cavo- or ileomesenterial anastomoses in children with previously performed splenectomy and in a group of comparison. Perfusion of the liver was found to decrease: in the least degree after splenorenal anastomosis and in the greater degere after cavo- and ileomesenterial one. It was established that all kinds of shunts ensured function of hepatocytes.

Child↗
PubMed1987

[Hepatic scintigraphy using 99mTc-colloid in liver cirrhosis in children].

A total of 26 children aged 2 to 14 with the initial (6), formed (14) and terminal (6) stages of liver cirrhosis were examined by a method of radionuclide scintigraphy with 99mTc-colloid. 34 children aged 7 to 14 examined in the catamnesis of virus hepatitis, were controls. A set of indices characterizing function of the reticuloendothelial system (RES), the effective hepatic blood flow, metric parameters of the liver and spleen were obtained from an analysis of the curves of the heart, liver and spleen area, and digital imaging of the liver with the marked costal arch. It was shown that at the initial stage of disease indices of the time course of the radioactive colloid were of compensated nature. Spleen function was elevated, liver and spleen sizes were increased. The formed stage was characterized by the signs of subcompensation of liver function: changes of indices of RP retention in the blood, a decrease in the indices of the total and hepatic radioactive colloid. The terminal stage was characterized by marked disorder of liver RES function which was not compensated for by a high splenic uptake, image deformation and focal RP distribution. Irrespective of a stage of disease the syndrome of portal hypertension was shown to manifest itself in splenomegaly and an increase in the radioactive colloid uptake by the liver over 15%. The accuracy of the set of signs was 90%.

Adolescent↗
PubMed1986

[Various problems of dynamics of the defense mechanisms of the body, the mechanism of development of infection and formation of metastases during infection].

Based on the study of the bactericidal activity of the purulent fluid and cytograms of 55 patients with suppurative processes and 19 patients with sepsis the authors explain the character of the antimicrobial "struggle" of the macroorganism in the infected wound and formation of septicopyemic metastases during sepsis. A test for diagnosing sepsis is suggested.

Arthritis, Infectious↗