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Biomedical subjects

S P Hersh

Publications and source records attributed to S P Hersh.

17 recordsLinked to original sources
PubMed1993

Immunological responses of breast cancer patients to behavioral interventions.

This article reports the results of an 18-month study of immune system and psychological changes in stage 1 breast cancer patients provided with relaxation, guided imagery, and biofeedback training. Thirteen lymph node negative patients who had recovered from a modified radical mastectomy were randomly assigned to either an immediate treatment or a delayed treatment control group. Multiple pre-post psychological measures were performed. Significant effects were found in natural killer cell (NK) activity (p < .017), mixed lymphocyte responsiveness (MLR) (p < .001), concanavalin A (Con-A) responsiveness (p < .001), and the number of peripheral blood lymphocytes (PBL) (p < .01). No significant psychological changes were detected; however, reductions were seen in psychological inventory scales measuring anxiety. The results show that behavioral interventions can be correlated with immune system measures, thereby replicating the results of an earlier pilot study from our Center. Discussion is provided on differential T-cell and B-cell responsiveness to behavioral interventions.

Adult↗
PubMed1990

Pachyonychia congenita. Manifestations for the otolaryngologist.

When discovered, leukoplakia of the oral cavity is commonly an acquired lesion. Pachyonychia congenita is a member of a rare group of disorders in which congenital white lesions of the oral cavity are present. Additional findings of note to the otolaryngologist are described as well.

Humans↗
PubMed1980

Children with serious illness: behavioral correlates of separation and isolation.

The deleterious effects of separation have been demonstrated in experimental animal studies and in naturalistic case studies of children. In this study extensive observational and physiological records were obtained on four preschool children who were receiving chemotherapy for childhood cancer. The findings generally parallel those reported in the subhuman primate literature. The children's behavior followed a sequence of agitation followed by behavioral depression. The findings underscore the seriousness of parent-child separation and the need to develop intervention strategies to ameliorate these deleterious effects.

Adaptation, Psychological↗
PubMed1978

Sweden's approach to health screening for preschool children.

The findings of a recent study of the approach taken by Sweden to a perceived problem in that nation's child health care system are reviewed. The Swedish experience is discussed in terms of its application to the United States, with particular reference to EPSDT and the newly proposed Child Health Assessment Program.

Child Behavior Disorders↗
PubMed1975

Early childhood psychosis and bleeding during pregnancy. A prospective study of gravid women and their offspring.

Children with infantile autism and childhood psychoses were identified in the National Institute of Neurological Diseases and Stroke Collaborative Perinatal Study. They were matched with two control groups one of normal-IQ and the other of low-IQ children. Perinatal data, which had been collected prospectively, were then rated blindly. The relationship between uterine bleeding in mothers and their subsequently delivered children, who developed the syndromes of autism and childhood psychosis, was found to be significant. Mid-trimester bleeding was especially prevalent. The bleeding was usually minor and was not considered to be clinically significant at the time of occurrence. The results tend to corroborate 12 previously published retrospective reports indicating more perinatal complications in children who develop autism and childhood psychosis.

Abdomen↗