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Biomedical subjects

S P Gladkikh

Publications and source records attributed to S P Gladkikh.

At least 19 recordsLinked to original sources
PubMed2004

Effect of low-energy laser irradiation on the area of experimental myocardial infarction, lipid peroxidation, and hemoglobin affinity for oxygen.

The mechanism of antiischemic effect of low-energy laser radiation was studied in rats with experimental myocardial infarction taking into consideration the effect of laser on hemoglobin affinity for oxygen and intensity of lipid peroxidation. Low-energy laser irradiation for 15 min in vitro decreased the area of myocardial infarction, slightly reduced hemoglobin affinity for oxygen, and inhibited lipid peroxidation. Short-term low-energy laser irradiation did not reduce the area of necrosis, initiated lipid peroxidation, and increased superoxide dismutase activity.

Animals↗
PubMed1989

[Analysis of trace elements of the brain and liver tissues in Wilson's disease].

In a patients with extrapyramidal-cortical form of the Wilson-Konovalov disease, brain and liver tissues were tested for Ca, Cu, Fe, Ka, Mg, Mn, Mo, P, Pb, Se, Sn, Sz, Zn, S, using plasma emission spectrometry. The tissues autopsied from 2 cerebral hemorrhage victims served as controls. Hepatic Cu concentration was increased 24-fold (6.89 mumole/g of tissue dry weight); Cu accumulation in the brain cortex and basal ganglia were 10 times as high as control levels; hepatic (8.78 mumole/g) and brain cortical (2.23 mumole/g) Zn contents were higher than controls, respectively by factors of 2 and 1.7; hepatic S content (289.4 mumole/g) was 1.2 times the control level; Mn brain content was above the control value. Mg was below the appreciable amount in the brain that was not the case in control. On the contrary, Sr was detected only in basal ganglia and liver in the patient and not detected in control tissues. Pb content in the patient's liver was above the control level.

Adult↗
PubMed1989

[Role of electrolytes in the pathogenesis of arterial spasm and muscle cramps in varicose veins of the lower limbs].

The blood magnesium and calcium content and the blood flow in the limbs was studied in 68 patients suffering from varicosity, 42 of whom had trophic ulcers of the legs. It was established that diminished content of magnesium in blood serum contributes to the development of hypercalcemia, spasm of arterioles, and the occurrence of muscular convulsions and trophic disorders and thus plays an essential role in the pathogenesis of changes of the blood flow and trophic disorders. Administration of magnesium preparations in the preoperative period improved circulation in the limb and relieved muscular convulsions completely.

Calcium↗
PubMedDate not supplied

[Role of vitamins in the prevention of atherosclerosis].

Persons doing brain work and taking aerovit in three courses of 30 days each with intervals of 5-6 months were kept under observation over a period of 13-15 months. While improving the vitamin allowance the course-wise taking of aerovit helped normalize the lipids metabolism factors characterizing an increased predisposition to atherosclerosis, the favourable effect being traced for 4-5 months after discontinuance of the preparation ingestion. Repeated courses contributed to a further improvement of the lipoid metabolism. A tendency towards positive changes in the tonicity of the intracranial vessels was recorded, while in subjects with an increased pulse wave propagation rate along the elastic type vessels this tonicity was seen to decline. With the available data on the positive effect of aerovit upon the lipoid and protein metabolism and some clinical and instrumental findings serving as a background an inference is made that a prolonged (course-wise) application of aerovit can be of help in preventing the development of atherosclerosis.

Adult↗