Cutaneous aggressive osteoblastoma.
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Biomedical subjects
Publications and source records attributed to S P Cannavo.
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The prevalence of cutis verticis gyrata was studied in a psychiatric institutional population of 494 patients, the majority of whom were mentally retarded or had chronic schizophrenia. Twenty-two subjects (21 males and 1 female) were found to have primary cutis verticis gyrata, yielding a prevalence of about 4.5%. The frequency of the scalp disorder was 11.4% among mentally retarded patients and 1.7% in schizophrenic subjects. A cytogenetic study was performed on patients with primary cutis verticis gyrata. In 9 out of 21 subjects there was evidence of chromosomal fragile sites: 5 patients had fragile sites on the X-chromosome, in 2 there was fragility of chromosome 12 and in 2, fragility of chromosome 9. The fragile X-site is the genetic marker of the 'fragile X-syndrome', a sex-linked inherited disorder often associated with mental retardation and other neuropathological findings.
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Three cases of barber's hair sinus of the hand are presented. The lesion is produced by the penetration of extraneous short hairs into the interdigital spaces of the hand. The hairs produce an inflammatory reaction and foreign body granuloma. The clinical picture is usually benign but can be complicated by repeated infection which may require surgery. The structure of the lesions varies from epithelial-lined tract, cyst with surrounding foreign body reaction, to fibrotic cicatricial tissue. The exact reasons for the lesion are not known, but several theories are offered. It is, however, clear that since the 1970's Italian barbers have changed their methods of cutting hair, using their hands more than the customary instruments, i.e., combs, brushes, etc. The authors discuss the occupational problems due to the complications of disabling lesions.