Search PubMed⌕ Search

Biomedical subjects

S Otsuki

Publications and source records attributed to S Otsuki.

At least 181 records · Page 10Linked to original sources
PubMed1978

Induction of the six c/sec spike and wave by diphenhydramine hydrochloride in healthy male adults.

Diphenhydramine hydrochloride (DPHm) solution 1.5% was given intravenously to 375 healthy males (mean age; 23.8 years) at a rate of 30 mg/min. The dosages injected were 2 mg/kg (N=157); 1.5 mg/kg (N=94); 10 mg/kg (N=72); 0.5 mg/kg (N=52). As a result, the 6 c/sec spike and wave discharges (WSP) was found in 19.7%, 9.6%, 20.8%, and 15.4% of cases, respectively. Comparisons were made between the WSP incidence versus past histories and Cornell Medical Index results, and between WSP positive and WSP negative subjects. No significant differences were observed in any of these parameters.

Adolescent↗
PubMed1978

Anxiety symptoms of the patients with aortic arch syndrome.

We reported six cases of the aortic arch syndrome with brain symptoms. Two could be explained directly as an organic impairment of the brain. In the remaining four cases, however, the mental symptoms were considered to have a basis of "anxiety." They were easily precipitated by iatrogenic and other various environmental factors. The hyperventilation syndrome had a high incidence occurring in three out of the four cases of anxiety. Thus, it seems appropriate to interpret their symptoms psychosomatically. The production of brain symptoms may be due to psychosomatic mechanisms in many cases of the aortic arch syndrome.

Adult↗
PubMed1978

[An autopsy case of bilateral cavities in the temporal white matter and the striatum (author's transl)].

A 24-year-old female developed high fever and unconsciousness for several days at the age of 3. She was said to have meningitis. Subsequently her verbal development was markedly retarded so that she was kept at a deaf-and-dumb institute. At the age of 19, she was transfered to the mental hospital because she occasionally became very wild without any reasons. She suddendly died at the age of 24 due to paralytic ileus. Her autopsy showed bilateral cavities in the white matter of the anterior portion of the temporal lobes and the striatum. Microscopically, the tissues around the cavities were necrotic and devastated with loss of neurones. Glio-mesodermal reaction was mild. Besides marked thickening of meninges and micropolygyria of the cerebellar hemispheres were demonstrated.

Adult↗