Measurements of blood lead by atomic absorption spectrometry.
Explore the source record for details and available documents.
Blood Specimen Collection↗
Biomedical subjects
S Nomoto
Publications and source records attributed to S Nomoto.
Rapid analysis of nickel in serum and whole blood by electrothermal atomic absorption spectrophotometry.
A method is described for analysis of nickel in serum and heparinized blood. After the sample has been subjected to protein precipitation with nitric acid and heat, nickel in the protein-free extract is measured by electrothermal atomic absorption with Zeeman background correction. The method is more sensitive, rapid, and convenient than previous techniques, and less subject to nickel contamination. Nickel concentrations in serums from New Zealand rabbits (mean +/- SD) average 4.0 +/- 2.5 micrograms per L, range = 0.9 to 11.9, N = 30; these results agree with measurements by the International Union of Pure and Applied Chemistry (IUPAC) reference procedure ( corr . coef . = 0.98). The following values are reported for nickel concentrations in serum and whole blood from healthy adult persons living in central Connecticut: serum, 0.46 +/- 0.26 micrograms per L, range = 0.1 to 1.3, N = 39; whole blood, 1.26 +/- 0.33 micrograms per L, range = 0.6 to 1.8, N = 30. This method is suitable for routine use in clinical and industrial laboratories.
Adult↗
Adverse effect of antipyretic agent on serum zinc.
To study the pathogenesis of the zinc deficiency that is sometimes found postoperatively, the serum concentration of zinc was determined in 35 patients before, during, and after thoracoabdominal surgery. Preoperatively, a serum zinc level below 60 micrograms per 100 ml was recorded in four of 16 patients tested and was associated with severe anorexia. Postoperatively, the serum zinc level was significantly reduced for up to four days, when the patient was unable to eat. After the start of oral feeding, the average serum zinc level returned to normal. The serum zinc level decreased rapidly in two patients after bouts of severe sweating produced by an antipyretic agent (diclofenac). In another patient, the serum zinc level decreased rapidly following the loss of a large volume of intestinal fluid via an intestinal stoma. Factors leading to low serum concentrations of zinc thus include anorexia, operations, antipyretic agents, and the loss of intestinal fluid.
Abdomen↗
Intraportal endovascular ultrasonography as a new diagnostic procedure in pancreatic surgery.
BACKGROUND/AIMS: This presents the results of a prospective study on the use of intraportal endovascular ultrasonography (IPEUS) as a screening tool for pancreatic carcinoma. PATIENTS AND METHODS: Twenty-four patients with pancreatic cancer (17 head, 7 body) were studied for portal vein invasion using intraportal endovascular ultrasonography (IPEUS). In 22 cases, IPEUS was performed intraoperatively from the superior mesenteric venous route with an 8-French, 20 MHz intravascular ultrasound (IVUS) catheter, in two cases preoperatively from the percutaneous transhepatic route with a 6- French, 20 MHz IVUS catheter. The sonographic criterion for detection of portal venous invasion was obliteration of the echogenic band of the portal vein. The IPEUS results were compared with those of CT and portography. RESULTS: Vascular invasion was confirmed with resected specimens in nine cases and with operative findings in three patients. For diagnosis of portal venous invasion, the sensitivity, specificity, and overall accuracy of IPEUS were 100%, 91.7%, and 95.8% respectively. For portography, the equivalent values were 66.7%, 75%, and 70.8%, while those for CT were 75%, 66.7%, and 70.8%.
Aged↗
Intraoperative quick immunoperoxidase staining: a useful adjunct to routine pathological diagnosis in pancreatic carcinoma.
BACKGROUND/AIMS: This paper presents the results of a study comparing conventional and quick immunostaining. This paper aims to introduce the reliability of the immunoperoxidase method for rapid intraoperative pathological diagnosis of pancreatic cancer and the quick staining method. MATERIALS AND METHODS: Intrapancreatic extension and intraperitoneal spread of pancreatic duct cell carcinoma were evaluated by both conventional and quick immunostaining using antibodies against cancer-associated antigens CA19-9, DUPAN-2, and CEA for intraoperative pathological examination during the course of laparotomy. RESULTS: For the surgical cut margin, malignant lesions were identified in six of 30 cases by H-E staining. However, cancer cells were detected in 14 of 30 cases by the immunostaining method. On peritoneal washing cytological examination, malignant cells were recognized in four of 27 cases by conventional cytology. In two other cases, positive immunocytochemical findings were noted, and these clinical courses were suggestive of the immunostaining results. CONCLUSIONS: This immunostaining method was particularly useful in defining cancer cells surrounded by dense fibrous connective tissue and a very small number of cancer cells within the mesothelium, in which malignant cells are usually difficult to identify by conventional staining. Thus, the application of such immunostaining, together with conventional staining, on the cryostat sections of biopsy or on the peritoneal washings may provide sensitive information for intraoperative pathological examination and for selection of the appropriate surgical method.
Adult↗
Postoperative delayed emptying in pylorus-preserving pancreatoduodenectomy using pancreaticogastrostomy: comparison of the reconstruction position.
BACKGROUND/AIMS: We frequently use pancreaticogastrostomy after pylorus-preserving pancreatoduodenectomy (PpPD). Although it is a useful and effective technique, it sometimes requires prolonged delayed emptying. We considered the best position for pancreaticogastrostomy in such a way as to reduce this period of delayed emptying. MATERIAL AND METHOD: From 1991 to 1996, 17 patients whose blood sugar was controlled and who were kept on H2 blocker were selected from among 25 patients who underwent PpPD and were reconstructed by pancreaticogastrostomy. We investigated the history of the relationship between reconstruction position and delayed emptying, reconstruction position and minor leakage, minor leakage and delayed emptying, reconstruction position and stomach mobility without leakage. RESULTS: The delayed emptying was shorter for a reconstruction position in the area above the angulus rather than below it. CONCLUSION: The results suggest that the area above the angulus is the preferred site for pancreaticogastrostomy after PpPD.
Adult↗