Search PubMed⌕ Search

Biomedical subjects

S Nitta

Publications and source records attributed to S Nitta.

At least 181 records · Page 10Linked to original sources
PubMed1987

[A case of angiosarcoma of both breasts].

A 19 year-old female, complaining of gigantic tumor on each breast and hemorrhagic diathesis, was admitted to our hospital. Laboratory data and clinical findings suggested the presence of DIC. Bilateral mastectomies reduced the bleeding tendency within a week. In conclusion, removal of the tumors was effective to avoid fatal hemorrhage.

Adult↗
PubMed1986

Branching architecture of canine pulmonary arteries: a quantitative cast study.

The purpose of this investigation is to analyze the branching pattern of pulmonary artery. The excised right lower lobes of six mongrel dogs were fixed by perfusion with 1.2% glutaraldehyde solution. Pressure of the pulmonary artery, vein and airway were controlled during perfusion. After fixation, resin was injected manually into the artery. When resin was completely polymerized, the lung was placed in 15 N NaOH solution to remove lung tissue. The diameters and lengths of branches were measured by stereomicroscopy. The results obtained were as follows: The basically dichotomous pulmonary arteries showed not only fairly regular dichotomies but monopodies, in the latter of which the diameter of parent branch was almost the same as that of its larger daughter branch. The diameter of monopodial branch was less than 500 microns, even when the parent branch was a large central segment. In arteries of over 1,000 microns in diameter, 75% or more of branchings were monopodies, whereas in small arteries of 200-300 microns in diameter, half the bifurcations were monopodies. At a bifurcation, the average daughter-to-parent diameter ratio was 0.8-0.9 for the larger daughter branch and 0.5 for the smaller one. The average length of branches was in proportion to their average diameter.

Animals↗
PubMed1985

Non-invasive estimation by cross sectional echocardiography of myocardial damage in cardiomyopathy.

Retrospective and prospective studies of high resolution cross sectional echocardiograms were undertaken in order to establish an ultrasonic method for the non-invasive estimation of degeneration and fibrosis of the endomyocardium in cases of cardiomyopathy. When the echocardiograms of the ventricular wall were compared with the histological specimens intense abnormal echoes were seen at the sites of myocardial degeneration and fibrosis of the ventricular wall. The abnormal echoes classified into five types: types I, II, III-1, III-2, and III-3. Type I and type III-1 echoes were the strongest followed by those of types II and III-2, and then those of type III-3. The intensity of the abnormal echoes was 5-20 decibels stronger than that from intact tissue and was closely related to the consistency and density of the diseased tissue. These findings strongly suggest that the boundary between degeneration or fibrosis and the intact normal myocardium was the source of the abnormal myocardial echoes and that the extent and the pattern of the distribution of the sites of degeneration and fibrosis in the myocardium were reflected in the echo patterns. Thus the tissue characteristics of the sites of degeneration or fibrosis of the myocardium may be determined non-invasively by measuring the echo intensity.

Adolescent↗
PubMed1985

[Pulsed Doppler evaluation of left ventricular pressure and pressure difference in hypertrophic obstructive cardiomyopathy].

To assess the patho-physiological severity of hypertrophic obstructive cardiomyopathy (HOCM), the systolic pressure differences caused by the functional stenosis across the outflow tract of the left ventricle must be evaluated. The present study explored and proposed a non-invasive method predicting the pressure difference across the intraventricular obstruction and the pressure proximal to the obstruction by using pulsed Doppler technique, guided by simultaneous two-dimensional echocardiography. The ultrasonic equipment recently developed in our laboratory was used. It consisted of a 3.0 MHz pulsed ultrasonic transducer with a 4.4 KHz repetition rate and a mechanical sector scanner equipped with a single concave transducer 1.3 cm in diameter having a 70 mm radius of curvature. The sample volume was approximately 3 X 3 X 3 mm. Doppler signals obtained were subjected to a real-time analyzer with a fast Fourier transformer, and were simultaneously recorded on a thermal recorder as a spectral display together with an M-mode echocardiogram, lead II ECG, phonocardiogram and mechanocardiogram. Ten adults with HOCM were the subjects in the present study. For six of the 10, good pressure tracings were obtained. The pressure differences estimated by the maximum velocity as measured from the Doppler signals at the left ventricular (LV) outflow tract and the pressure gradients as obtained by cardiac catheterization were subjected to correlative analysis. Prior to investigating the pressure differences, the site and mechanism of the outflow obstruction in HOCM were studied in two cases using two-dimensional echocardiography in the longitudinal- and short-axis views. The obstruction was produced during systole by posteroinferior displacement of the hypertrophied interventricular septum and by abnormal anterosuperior movement of the hypertrophied, and elongated anterior or posterior papillary muscles. Thus, a concentric and centripetal narrowing was formed at the midportion of the outflow tract. In some cases, a bottle-shaped chamber was clearly observed in the apical area. Ultrasonic Doppler examinations were performed by the apical approach. Flow velocity patterns in the apical region or proximal to the obstruction had two peaks with a narrow spectrum in systole. At the distal portion or downstream the obstruction had a pattern with a narrow spectrum and a sharp single peak. To measure the maximum flow velocity, Doppler velocity patterns recorded immediately distal to the obstruction were used.(ABSTRACT TRUNCATED AT 400 WORDS)

Blood Flow Velocity↗
PubMed1985

[Assessment of ability to withstand lung resections and post-operative survival in patients with respiratory disorders and bronchogenic carcinoma].

Of 1192 lung resections in patients with bronchogenic carcinoma since 1952, the early post-operative mortality averaged 3.9%, whereas during the last ten years, it was 2.6% of 730 lung resections, including 159 (22%) pneumonectomies, 76 (10%) bilobectomies, 492 (67%) single lobectomies and 3 (0.4%) partial lung resections. In the latter, 352 (48.2%) and 75 (10%) had airway obstructive failure of FEV1.0 less than 70% and 55%, respectively, and, 56 (7.7%) and 9 (1%) represented preoperative hypoxia of PaO2 less than 70 torr and 60 torr, respectively. The ratios of pneumonectomies in these, being similar to those with better lung functions, the perioperative mortality was also similar. Our previously reported indices preoperatively to prove ability to withstand curative lung resections, being supported by these data, we attempted in a certain limited group of patients, extendingly to clear patients with critically poor predicted pulmonary vascular reserve pf 710-930 dyne . cm-5 . sec/m2 for lung resections, resulting in six elevenths of over one year survival. One must extend benefit of lung resection to patients with coexistence of bronchogenic carcinoma and respiratory disorder apparently severe enough to preclude resection surgery by critical assessment of the predicted pulmonary vascular reserve after lung resection.

Aged↗