[Disseminated intravascular coagulation in leukemia and other disseminated neoplasms].
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Biomedical subjects
Publications and source records attributed to S Nicoară.
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The course of two cases of severe aplastic anemia (AA) was followed up in two young male patients who, besides the conventional therapy, received perfusions with blood obtained from patients with polycythemia vera (PV). Case 1 received 4 units of PV blood from a unique donor. During the following week an obvious clinical relief, as well as increase of the peripheral blood values were recorded. Subsequently, the bone marrow was progressively repopulated with normal precursors and the peripheral blood picture reverted to normal. In case 2, 9 units of PV blood, obtained from two donors, were administered. During the next week a transient clinical and hematological improvement was obtained, but later on the progressive granulocytopenia and the infections led to exitus through a toxic-septic shock. It is assumed that PV blood may be a good replacing and a possible stimulatory therapeutic material, useful to overcome the early critical stage of severe AA.
The modern vitreous surgery has rapidly developed during the last 2 decades, becoming an effective part of the treatment, in most retinal detachments that cannot be treated by the classical means. This study points out the main types of retinal detachment in which vitrectomy is indicated, as its place in the complex therapeutical sequence. It is based on the studies of ophthalmologists with experience in vitrectomy is indicated, as its place in the complex therapeutical sequence. It is based on the studies of ophthalmologists with experience in vitreous surgery. If there continue to be controversies on vitrectomy's indications and moment, the fact that vitrectomy has radically changed the prognosis and therapeutical attitude in severe retinal detachments, is unanimously admitted. Most retinal detachments (the rhegmatogenous, uncomplicated one) continue to be treated by the classical means: scleral buckling+Rupture's blockage.
The purpose of the study is to point out the characteristic clinical, therapeutical and evolutive features in the acute ischaemic suffering of the optic nerve's preliminary portion. A retrospective study has been performed, on the patients with anterior ischaemic optic neuropathy (AION), hospitalized in the Ophthalmologic Clinic from Cluj-Napoca, between 1986-1994: 71 cases. The main functional (visual field, visual acuity) and ophthalmoscopic aspects are analyzed, as their evolution after treatment. Results are significantly better if corticosteroids are systemically used (43.3% improvement of the visual field) than in their absence (17.07% improvement of the visual field). The high percentage of failures (70%) proves the absence of a therapeutical method to cure or bring a significant visual function's improvement in AOIN.
The paper present the functional and anatomic results obtained in 376 retinal detachment operations done in the Ophthalmological Clinic from Cluj-Napoca. The following types of operations were done: cerclage Arruga, scleral indentation, surface diathermy, laser photocoagulation. The retrospective study revealed percentages of 73.41% the anatomic reapplication and 50% in functional recovery. The negative influencing factors of the prognosis were: aphakia, large and old retinal detachments, macular region affectation.
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The paper presents a case of autoimmune hemolytic anemia (AIHA) with warm IgG antibodies associated with Waldenström's disease in which in the stage of compensated hemolysis after treatment, there appeared a severe hemolytic attack induced by transitory cold agglutinins with high thermal amplitude. The case described is a novelty by the intrication of two autoantibody populations which causes autoimmune hemolysis. The difference from other similar associations is discussed.