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Biomedical subjects

S Neuenschwander

Publications and source records attributed to S Neuenschwander.

At least 109 records · Page 6Linked to original sources
PubMed1982

[Renal venous thrombosis in infants. Ultrasonic findings in 7 cases (author's transl)].

Ultrasonic examination was performed in 7 infants with renal venous thrombosis. Early findings included renal enlargement, increased echogenicity with a low cortico-medullary difference and very thin intra-renal excretory cavities. Thrombosis of the inferior vena cava was seen in one case. Ultrasonic follow-up was in agreement with findings on IVP. In favorable cases all findings returned progressively to normal. In cases with poor prognosis kidney size decreased but echogenicity and renal cavities remained unchanged. In addition, ultrasonic examination is useful in differentiating renal venous thrombosis from other causes of retroperitoneal masses in infancy.

Female↗
PubMed1981

[Echotomography in nephroblastoma and neuroblastoma of the lumbar fossa in childhood. Comparison with intravenous pyelography and computerized tomography (author's transl)].

The respective values of intravenous pyelography, ultrasound examination and computerized tomography are compared with the findings at surgery and with histological data in 28 children with malignant tumors of the lumbar fossa. Ultrasound proved to be of significant value in assessing the extent of the tumor. At the present time, computerized tomography is only indicated when intravenous pyelography and ultrasound examination fail to provide adequate information.

Angiography↗
PubMed1981

[Ultrasonic aspect of neo-natal adrenal hematoma. 7 cases (author's transl)].

The authors report 7 cases of neo-natal adrenal hematoma diagnosed by ultrasound. A traumatic delivery was found in 4 cases. In 4 cases a flank mass was palpated. In 3 cases the adrenal hematoma was asymptomatic, discovered by echotomography. I.V.P. showed a typical appearance in only 1 case out of 5. The first ultrasonic examination was performed between day 5 and day 12. It showed a fluid filled mass in 5 cases and a predominantly fluid mass in 2 cases. Both sides were involved twice. The ultrasonic follow-up 8 days later always showed a decrease in size, in 1 cases calcifications appeared. The authors compare their results with those of the literature and discuss the differential diagnosis with neo-natal neuroblastoma.

Adrenal Gland Diseases↗
PubMed1976

[The small left colon syndrome. 3 cases].

In the light of three cases of neonatal obstruction related to a small calibre descending colon, the authors review the main clinical and radiological signs and compare them with the data in the literature. This functional disturbance is related to immaturity of the intrinsic innervation of the colon which is especially common in low birth weight neonates or of diabetic mothers. Diagnosis is dependent upon enema using diluted uroangiographic hydrosoluble iodine contrast medium, which shows a disparity in calibre at the left colic angle. The differential diagnosis lies with Hirschsprung's disease. Functional ileus in premature infants, meconium ileus and the "small left colon syndrome" are related to the same pathogenisis: functional immaturity of the colon.

Colon↗
PubMedDate not supplied

Hepatic and splenic involvement in cat-scratch disease: imaging features.

Hepatosplenic involvement in cat-scratch disease, probably underdiagnosed, is characterized by multinodular lesions throughout the liver and spleen. Radiologic features of ultrasound, computed tomography, and magnetic resonance imaging are not specific. The key of the diagnosis relies on a history of cat or kitten contact. A specific serological test can confirm the diagnosis without invasive procedures such as biopsy.

Cat-Scratch Disease↗
PubMedDate not supplied

Synchronization of neuronal responses in the optic tectum of awake pigeons.

Multiunit activity was recorded in the optic tectum of awake pigeons with two electrodes at sites varying in depth and separated by 0.3 to 3.0 mm. Autocorrelation and cross-correlation functions were computed from the recorded spike trains to determine temporal relationships in the neuronal firing patterns. Cross-correlation analysis revealed that spatially separate groups of cells in the tectum show synchronous responses to a visual stimulus. Strong synchronization occurred in both superficial and deep layers of the tectum, in general with zero-phase shift. The response synchronization in the avian optic tectum resembles that observed in the mammalian cortex, suggesting that it may subserve common functions in visual processing.

Action Potentials↗
PubMedDate not supplied

Carrier detection of ovine hemophilia A using an RFLP marker, and mapping of the factor VIII gene on the ovine X-chromosome.

Ovine hemophilia A is an X-linked recessive bleeding disorder. For diagnostic purposes, restriction fragment length polymorphism (RFLP) analysis in the region of the factor VIII (F-VIII) gene was carried out using human F-VIII gene probes. The probe St14, known to detect a highly polymorphic region that is closely linked to the F-VIII gene in humans, hybridized nonspecifically with DNA from sheep. Searching for intragenic RFLPs, the entire 9.0-kb coding sequence of the human F-VIII was used as a probe. Using the 1.8-kb SstI/KpnI F-VIII cDNA probe for hybridization, an MspI-RFLP with allelic bands of 5.8 kb (A1) and 4.2 kb (A2) was detected. A1 was in linkage phase with the mutated allele responsible for hemophilia A. The F-VIII locus in the sheep genome was assigned to the long arm of the X-chromosome in the region Xq24-q33, using in situ hybridization with a 3-kb human F-VIII cDNA probe to QFQ banded sheep metaphase chromosomes.

Animals↗
PubMedDate not supplied

Clustered breast microcalcifications: evaluation by dynamic contrast-enhanced subtraction MRI.

OBJECTIVE: Our goal was to evaluate dynamic contrast-enhanced subtraction MRI in the diagnosis of isolated clustered calcifications of the breast. MATERIALS AND METHODS: One hundred seventy-two patients underwent surgical biopsy for isolated clustered breast calcifications. Their mammograms showed round (n = 88) or linear/irregular (n = 84) microcalcifications. All patients had a preoperative Gd-DOTA-enhanced subtraction dynamic study. Any early contrast enhancement in the breast parenchyma concomitant with early enhancement of normal vessels was considered positive. RESULTS: Fifty-eight in situ carcinomas, 22 invasive carcinomas, and 92 benign lesions were found at histological analysis. Dynamic MR sequences showed early contrast enhancement in 76 of 80 malignant lesions (sensitivity 95%) and in 45 of 92 benign lesions (specificity 51%). Two invasive and two intraductal carcinomas did not show early contrast enhancement. Three independent observers agreed in rating early contrast enhancement in 143 of 172 lesions. CONCLUSION: Poor specificity limits the diagnostic accuracy of dynamic contrast-enhanced subtraction MRI in distinguishing benign from malignant microcalcifications on mammography.

Adult↗
PubMedDate not supplied

Factor VIII in blood plasma of haemophilic sheep: analysis of clotting time-plasma dilution curves.

The sheep haemophilia A, recently described in a flock of White Alpine sheep, is probably caused by the production of a less potent mutant of factor VIII (F-VIII). Other potential mechanisms, such as drastic reduction (or lack) of F-VIII production, or occurrence of an F-VIII inhibitor, are less likely. This conclusion was based on the analysis of plasma dilution-clotting effect relationships in normal female (anestrous, non-pregnant) sheep, female carriers of haemophilia A, and afflicted male sheep. A response model underlying the analysis was suggested, its validity tested, and a mathematical analysis suitable for routine evaluation procedure recommended.

Animals↗
PubMedDate not supplied

[Thrombosis of the superior longitudinal sinus in the treatment of lymphoma in children. 4 case reports].

The authors report four cases of children, beginning a treatment for a lymphoma; these children present neurological symptoms, which CT scan and digitalized intravenous angiography have shown to be connected to superior longitudinal sinus thrombosis. They are reexamining similar cases described in the literature, related to leukemias, lymphomas and other cancers, and describe their angiographic and CT scan appearance. The pathogeny of these complications is considered but is improven.

Adolescent↗